BigEasy said:
W6, and Remy, how do you feel about claims by food processors that maltodextrin rich products, like Splenda, have no insulin response? I have heard the arguments that a one teaspoon sugar-equivalent serving of Splenda is insufficient to evoke insulin responses. Is this correct?
From what I have read, Sucralose (brand name Splenda) is a new sweetener that is derived from sugar.
- regarding its insulin responce -
.::Glycemic effect of a single high oral dose of the novel sweetener sucralose in patients with diabetes. (Mezitis NH, Maggio CA, Koch P, Quddoos A, Allison DB, Pi-Sunyer FX.)::. The study was done to examine the effect of a single high oral dose of the noncaloric sweetener sucralose on short-term glucose homeostasis in patients.
RESULT:Regardless of the type of diabetes, areas under the curves for changes of plasma glucose and serum C-peptide levels after sucralose administration were not significantly different from those after placebo.
CONCLUSION: The present results support the conclusion that sucralose consumption does not adversely affect short-term blood glucose control in patients with diabetes.
.::Repeated dose study of sucralose tolerance in human subjects.(Baird IM, Shephard NW, Merritt RJ, Hildick-Smith G)::.Two tolerance studies were conducted in healthy human adult volunteers. The first study was an ascending dose study conducted in eight subjects, in which sucralose was administered at doses of 1, 2. 5, 5 and 10mg/kg at 48-hour intervals and followed by daily dosing at 2mg/kg for 3 days and 5mg/kg for 4 days. In the second study, subjects consumed either sucralose (n=77) or fructose (50g/day) (n=31) twice daily in single blind fashion
RESULT: No adverse experiences or clinically detectable effects were attributable to sucralose in either study. Similarly, haematology, serum biochemistry, urinalysis and EKG tracings were unaffected by sucralose administration. In the 13-week study, serial slit lamp ophthalmologic examination performed in a random subset of the study groups revealed no changes. Fasting and 2-hour post-dosing blood sucralose concentrations obtained daily during week 12 of the study revealed no rising trend for blood sucralose