The issue is as it always is - the answer they want (most forums).
Or the truth (here we are). 99% of users get fat. Avoid
You hear alot of people saying that insulin is NOT anabolic and has no purpose for muscle building and will just make you fat.
well.... consider these thoughts.
Insulin is what we call a glucose disposal agent, essentially it 'opens' up the cells to receive glucose and other nutrients (which includes amino acids and also other hormones and drugs in the blood) , this causes a drop in blood glucose levels (we know as hypoglycaemia).
Another mechanism is the effects on IGF serum levels, IGFBP serum levels and IGF Receptor affinities . We know that all insulin types can increase IGF levels, most to a significant degree, they also lower levels of IGFBP - increasing availability of IGF, another great feature of insulin is it can actually bind to the IGF-1 Receptor , especially insulin glargine which binds to the IGF Receptor with an affinity higher than that of any other insulin currently.
We also have studies indicating that insulin may decrease SHBG (sex Hormone bindings globulin) increasing availability of testosterone. We believe that insulin is antagonistic to growth hormone meaning that when one is raised the other is lowered meaning with exogenous insulin, growth hormone levels decrease, which is why GH is recommended with insulin and vice versa. MK677 is another combo that works well.
So there are many mechanisms of growth with insulin usage, 1: Nutrient shuttling, increasing the nutrients available to muscle cells, 2: IGF, increasing IGF levels, decreasing IGFBP and binding to its Receptor can cause hugely Anabolic affects to muscle cells, 3: Possibly decreasing SHBG, increasing testosterone, and other androgenic steroids availability to bind to receptors.
That’s pretty anabolic to me!
I do not push using insulin and I actually do not like taking it because I cannot be flexible with the timing of my meals and having to eat. I will refute those that say that it just makes you fat. Excerpts from GearHead and all of this is medically sound.
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