If you're just starting out or to put it a better way, if you can't lift really that much then I would use post-exhaustion, or in other words do the compound first and then finish the muscle with an isolation exercise, eg squat first then do a set of heavy leg extensions.
After a while of doing that you'll end up having to lift ridiculous amounts to progress and it can stress your joints, especially if you have some inherent weakness, say in your knees or somewhere. Then it would pay you to use pre-exhaustion, so that you wouldn't need to lift as much in your compound movement because the primary muscle you want to train is already half fried.
But, like I said, if you can't really lift that much in your compound movements anyway, I'd recommend doing them first because, as their name suggests they train more than the primary muscle and stimulate a whole block of muscles to grow, so if you use pre-exhuast you are limiting the stress placed on those other muscles other than the primary because you are making the primary the weak link. This is not what you want if you're at a time when you want to lift as much in your compund movements as you possibly can to make your body grow quickly.