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napsgear
genezapharmateuticals
domestic-supply
puritysourcelabs
Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

IGF in post cycle -- needed??

Hello everyone I am a 28 year old male about to start a 12 week cycle. The cycle I want to start is from: isteroids beginner cycle

Test E weeks 1 - 12 || 500mgs/week
Dianabol week 1 - 4 || 25mgs/day
Arimidex week 1 - 4 || 1mg day & week 5 - 12 || 0.5mg day

POST CYCLE WEEK 14 - 18
Arimidex (week 14 and 15 || 0.25mg ED) & (week 16 and 17 || 0.25mg EOD)
Clomid (week 14 || 100mg/day) & (week 15 ||100mg/day) & (week 16 || 50mg/day) & (week 17 || 25mg/day) & (week 18 || 25mg/day)
IGF-1 (week 14 || 60mcg/day) & (week 15 || 40mcg/day) & (week 16 || 40mcg/day)


however the only thing I would like to change would be removing the igf. Why? honestly I don't feel im educated enough on peptides and feel that there is a lot that can go wrong with using this if I don't know what I'm doing. So what I'm asking is everyones input on the cycle excluding the igf. If it should be replaced etc etc. I feel that post cycle is the most important part of a cycle and I want to make sure there is no doubt in my mind that I have a good post cycle ready before even starting a cycle. Thank you guys for your input.
 
1mg dex ED is too much. 1mg E3D is more like it. IGF LR3 in pct will almost make it an extension of the cycle itself. it is amazing and I will never be in pct without it. yes you are right about peptide knowledge, you want to know what your doing with LR3 cuz it is similar to slin. but it is much safer.

chemical need is having a sale now on it. pick up a bottle and pm me. Il walk you threw it, and show you where to go for the proper info. read, research all you can in the mean time.
 
I've been to lots of forums and sites researching igf1. Many people keep asking me what igf has to do with "jump starting your natural testosterone". Lots of other people seems to believe igf does nothing like its a placebo or something.... Anyway I would like to use this drug to help in pct!! However I do not want to go above 50mcgs EOD due to perma-gut. Also the information that I found states:

Code:
IGF-1 increases steroidogenic acute regulatory protein  (sTAR), and cholesterol side chain cleaving enzyme (CYP 11A). These  are both rate-limiting steps and are critical factors for converting  cholesterol into hormones, such as testosterone. IGF-1 also has the  ability to increase the concentration of steroidogenic enzymes in the  testes, such as 3b HSD. IGF-1 can also increase the testes  sensitivity to LH and HCG by increasing the number of LH  receptors.

These positive effects on testicular function make IGF-1 an ideal drug  for PCT. A dose of IGF-1 Lr3 at 80mcg/day, split two times per day,  would likely be the most cost effective dose.

But the dosages seem a bit to high judging by this:


Code:
The difference between rhIGF-1 and Long R3 is that the Long R3 does not  get bound by binding protein and thus is 100% active whereas you do lose  a great % of whatever amount of rhIGF-1 you inject to IGFBP3.
 
While technically it is true that if you inject a large amount of the  rhIGF-1 it will have almost only localized effect, it is so because the  "excess" that does not bind to cells in the muscle in which it is  injected is rapidly bound up by IGFBP3 and thus rendered unusable by  cells elsewhere. It would be much much better in such a case to inject a  smaller amount and not have ANY excess that gets bound up by IGFBP's.
 
And while technically it is true that if you inject a large amount of  Long R3 IGF-1 in a muscle, it will first bind to the nearest available  receptor, and spread, binding to more and more receptors and not be  bound up and neutralized by IGFBP's, meaning that it will travel all  through your body and grow all kinds of tissue. This is called the  systemic effect of IGF-1. Therein lies the only distinction in terms of  BOTH half-life and localized/systemic effect between the Long and the  human varieties.
 [B]
What does all this mean?[/B]
 
It means that technically, for the part of the muscle in which you  inject, THERE IS NO DIFFERENCE BETWEEN rhIGF-1 and Long R3 IGF-1. They  both have the EXACT SAME LOCAL EFFECT. But rhIGF-1 gets neutralized  quick, whereas Long R3 gets to float around until it finds a receptor.
 
 [B]What does all this tell us?[/B]
 
It tells us many things. Let's start with what we want, then see where  that leads us. What do we want? Bigger muscles. More muscle cells that  we will later grow with exercise and gear. A pump? Fatloss? Yeah, right.  You can get a pump with a good "pump" product for a quarter of the  price of IGF-1. Fatloss? Clen/Alb and T3/T4 will give it to you again at  a fraction of the price of IGF-1. More muscle cells, you can ONLY get  with IGF-1 (and MGF too). Nothing else will give it to you and if you  are using IGF-1 for anything else, you are misusing it. More muscle  cells is CLEARLY the best use for IGF-1.
 
 [B]What does all this tell us?[/B]
 
It tells us that we should use IGF-1 to make more muscle cells. It's the  only thing that can give it to us and more cells is more growth, which  is our goal.
 
 [B]What does this tell us?[/B]
 
The localized effects are the best. Long R3 IGF-1 can float around your  body and attach to anything that has IGF-1 receptors. The intestines is  the place that has the MOST IGF-1 receptors and it also happens to have  lots of blood flow. Injecting large amounts of Long R3 ENSURES that you  are growing your intestines. Remember, more cells doesn't equal more  size right away. Wait a bit, and see them grow.
 
 [B]What does this mean?[/B]
 
It means that if you are injecting upwards of 50mcg of IGF-1 you are  growing your intestines. Yes you are also growing muscle and you may be  getting leaner in the process. Your waistline looks trimmer. Nice. A few  months down the line, your new intestinal cells will be of their full  adult size and you will have acquired the perma-bloat look. Guaranteed.  Maybe not Coleman-size perma-gut, but SOME perma-gut and it will keep  growing. Guaranteed. Just as your new muscle cells can keep growing and  growing IF you pin IGF-1 in a way to maximize new muscle cell creation.
 
 [B]HOW?[/B]
 
Heavy resistance exercise strongly upregulates the IGF-1 receptors on  the stressed muscle. That means that after your workout, the muscles you  trained are at their BEST STATE for receiving IGF-1 and growing many  new cells. That's when you pin. This upregulation of IGF-1 receptor  during exercise is short-lived. The science is not readily available so I  am unable to quote a paper, but within 60 minutes of the last set, the  receptors are back at baseline. This means, PIN IMMEDIATELY POSTWORKOUT  and you will get your new muscle cells. PIN A LESSER AMOUNT and you will  get only new MUSCLE cells out of your IGF-1. Pin more and you will grow  other things, including stuff you wish you didn't grow.
 
 [B]What else?[/B]
 
All the talk about IGF-1's half-life is UTTER BULL****. It is  technicality without any real-world applicability. Yes rhIGF-1 has a  "short half-life". But what does it mean? It means that it is either  taken up by a cell receptor or bound up by a binding protein in short  order. Does it mean that 20 minutes after the IGF-1 is pinned you should  pin more because "blood levels are low"? Not by any means. Once it's  activated a cell receptor, that's where it initiates a cellular response  that will take about 72 hours to be complete and which will consume  lots of energy. So the half-life of 20 minutes means NOTHING BECAUSE THE  EFFECTS STILL LAST 72 HOURS ALL THE SAME.
 [B]
What about Long R3 IGF-1?[/B]
 
Yes technically it has a longer half-life. Why? Because it either gets  rapidly taken up by a cell receptor or... Just floats around. Until it  can find a receptor or is destroyed by the immune system or some other  metabolizing mechanism. BUT THIS MEANS ***NOTHING***!!! Why does it mean  nothing? BECAUSE once it attaches to a cell receptor, it initiates a  cellular response that will take about 72 hours to be complete. THIS  CELLULAR RESPONSE IS ALL THAT INTERESTS US. Not "blood levels", that's  utter bull****. As a matter of fact, the one thing YOU DO NOT WANT IS  FOR BLOOD LEVELS OF IGF-1 TO BE ELEVATED. Because that means you are  growing everywhere and this means first and foremost your guts. Sure it  feels like it's working while you're on. Just you wait 9 months and see  that you look like Craig Kovacs. Bravo, you now have the biggest  intestines in the world.
 
Half-life means nothing. Localized vs systemic = bad argument. You want  localized effects. Period. You get them by pinning immediately  postworkout. Period. End of argument.

My goal before I take that first shot is to find a post cycle therapy that will work. I've gone forum to forum site to site and everyone seems to neutralize everyone else's research and ideas. Nothing is worst that spending hundreds on gear, spends hours in the gym. getting great gains and feeling amazing then crashing after and losing everything. I appreciate all help and take everyones advice into consideration and blow no one off. Thank you for your time and thank you too gymrat. Hopefully I can get some good answers or at least conversations going on this.
 
I like your cycle, only things I'd change are lower dosages on the dex (knock it up again if you feel estro sides coming on) and also the clomid, 50mg a day tapering down to 25 over four weeks should be fine. I'm interested in this PCT strategy also, anyone have experience with IGF?
 
you should not even consider running something when you are not educated enough on it... you said you felt you did not know enough about igf to run it so then I would advise againast it... now if you start doing reasearch and truly understand it and how to use it, then that's another story... it will be a good addition to your pct but you need to have a prolonged usage of it... you will also need to realize that your carb consumption will need to increase while taking it and you will need to monitor this... study up and make sure its right for you... from the sounds of it, you are a studier, so just continue with that and then make your decision...
 
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