I'm curious, how are you guys planning to manage daycare for the kids and what about healthcare for all of you?
Satisfaction in your career is incredibly important. When I was young I had to take whatever work I could find to pay the bills and it became a career by accident which kind of sucked the joy out of life ... but I do agree with Miplank about being there for the rugrats. Generally speaking kids hit their teen years and can turn into vipers towards their parents until they get into their 20s, IOW, being around for the high school years ain't so important (just lock up the liquor). They stop needing you or wanting your company unless they want cash or to be driven somewhere from about 12 to 18. Little kids, OTOH, want to play with their parents and be around them. You really only get to enjoy that for such a brief time.
Of course, Glad, you do seem to have a tendency to land butter side up no matter what you do so best of luck.