My DXM experience

[BrothaBill]

when i did it i did 3/4 a bottle and then an hour later i did another half a bottle.

yeah i got robo max stregnth cough. dxm only.
me and my buddies and trying get some ketamine or pcp.

Yeah, some like to split the dose especially in the beginning. Doesnt really matter I spose.
I dont mess with illegal stuff, people that I know that have compared K with a higher plateau experience say that dxm is by far more enjoyable. But to each his own, it can be a love it or hate type of thing depending on the individual. Plus dxm is cheap and legal in the US and most countries, you cant flunk a urine test and you can control your experience well if you adjust dose/kg.

Note: At higher plateaus like 3, 4 or sigma(named after the sigma activity of the brain) its recommended to have a sitter. Do NOT use alcohol with this, at larger doses DXM depresses the respiratory system and it will potentiate strongly with alcohol which makes it dangerous. Dont want to end up on the omega plateau.

Evidence of brain damage has not been established conclusively and alot of people who have thought that base it on internet chat on discussion boards because it was hypothesized by William White who wrote the FAQ sections on the boards. Stating that it may cause Olney's lesions and NAN in the brain which was just speculation by one and he stated that although he believes that its possible *his words: "in RARE cases"* he had to admit that Olney's lesions have never been found in humans, ever. It was his hypothesis and it has been discounted by several others, yet its still brought up frequently. There is actually research being done on DXM to prove that it actually can prevent brain damage.
I dont want to say William White is full of shit with the olney's lesions and NAN.
But he is.
He actually has contributed greatly to the safe use of DXM, but his conclusions at times are ludicrous. Yet his views are bandied about as if he were an omnipotent god who doesnt need evidence based research.He uses alot of what he has perceived to have happened to him as evidence as to the effects of longterm use of DXM are. I suspect that he was weird as fuck well before ever using DXM.
As for brain damage one could make the same claim for long term use of marijuana but there friends would probably laugh at them when they argued it.
As with any drug, disassociatives should not be used on a frequent basis or at a very high dose very close in proximity. Most animal studies that infer that damage may occur are at aneshetic levels, which people do not use for recreational purposes. People who may be susceptible to prior brain abnormalities may have them exhibit them. There is an enzyme that some lack that is needed with dxm so someone who decides to do this should start with a small dose to be sure. There are also instances where people who had preexisting conditions such as neural deficits or schizophrenia to name a couple of examples where dxm use had an adverse effect.

If someone chooses to use a substance that is their choice at the moment with this compound as the government has not deemed it to be illegal. There are safe ways and there wrong ways to use it just like steroids. Best to be informed on the matter and an open discussion can help that.

There is what is called the 50 trip limit to DXM where after that most are not able to experience the effects anymore. That is a built in limit to using longterm and limits risk of abuse, it simply becomes pointless as you dont feel the effects to most. There are cases though of long term every day use among addicts. Addiction is bad with any substance, it is of course hard to compare that to recreational use. Some have reported issues while others reported to have been perfectly fine after such abuse. One cannot scientifically infer, at least they havent been able to yet, that it was the dxm or a preexisting condition. There is alot of misinformation about dxm that is being spread to help combat the large rise in teenage users. Teenagers should never use disassociatives or any drugs, and though the campaigns have the best of all intentions by using deceptive claims about the drugs to scare and limit its use. It doesnt always fit the facts and usually backfires as the kids discover the truth and are more likely by nature to use them. Remember reefer madness from the sixties.
Drinking syrup can cause diarrhea and especially vomiting.
Tabs or powder do not.
One should read the FAQ by you guessed it, William White, on erowid or thirdplateau. Although he is a scientific hack at times, its outweighed by all the other good info he offers.
Easy solution, dont do drugs. Pot, alcohol, cocaine, steroids, dxm, K, X, etc... and you dont have to worry about any of this, if you do decide to use any of these substances as I assume some of you will b/c its your choice, then do it wisely and read about it.

 

[Debaser]

Horrific experience.

After puking a LOT, I saw my friend turn into a gargoyle, and crumble. Deciding that he would be of little help in such a state, I called one of my other friends, crying and saying that I was going to die.

Then I stumbled to the bathroom and proceeded to have my internal organs violently erupt from my anus.

Once was enough for me.

And to all you current and potential robo-tards out there, it causes substantial brain damage. Way more than most drugs.

 

[BUBBLES]

Interesting info on DXM!
Never heard of it.

 

[beefybull]

If you use Yohimbine-containing products, dont use them the same day as you drink syrup unless you want Olney's Lesions (brain damage). Theres articles about the dangers on the net. Yohimbine + DXM or DXM + some antihistamines can kill you. I think Claritin and some other shit might interact as well.

If you're going to do DXM, make sure to get products containing ONLY DXM. It's the only ingredient that will get you high and any syrup/pills containing multiple active ingredients can kill you or fuck your organs if you use them in the quantities needed for a DXM trip. Syrups, while tasting bad, offer a somewhat controlled release. Now they make strips similar to the Listerine strips, containing only DXM. I'd imagine they hit quick. Some out there can get the pure USP Dextromethorphan powder but I've never done it.

I tried Robitussin Liquigels (red 15mg pills, DXM-only). They come 20 to a bottle and I took 40 thinking the 600mg dose would be somewhat similar to a 480mg dose (vicks 44) I'm used to. I was really wrong. They hit super quick and it was more intense than any other DXM experience ever. I was also sick to my stomach for the first time ever from DXM. Probably the gelcaps or red dye(?). I called a friend to act as a designated driver b/c I would have wrecked my coupe if I would have driven then. I seriously thought I might die for a second it was so intense, I walked into a store while waiting for my friend, bought a bunch of water, drank it and then used the restroom.

Turns out the family was living in the back of the store or maybe the mom just brought the kids by but I had to navigate thru a small room filled with toys & people while trippin hard. I tried my hardest to puke up the shit in the bathroom but couldnt do it. After a while it plateaued (but still fairly intense) and I rode around with a friend and his woman. At one point they were fighting outside of an apartment complex and I was laying on the sidewalk watching clouds and listening to them bicker. I havent really done DXM since.

At those doses (600mg or less), the effects are really just a slight distortion of sight/touch/sound, reduced sense of pain, reduced coughing or none, your limb movement can feel slightly uncoordinated since you dont feel them as you would normally. This is the "robo walk" they are talking about above. The first time I ever did DXM, I could barely feel my legs, I thought it was kinda funny.

Note: DXM dilates your pupils like crazy, perhaps even worse than LSD, shrooms, or the phenethylamines (speedz, MDMA, & the 2C-family). Anyone watching for dilated pupils will know you're on something.

It's probably good to take a multivitamin & vitamin c a few hours before you do it as well.

 

[KillahBee]

did it once, drank the whole bottle in one shot. about 30 minutes later I was in bed wanting to die. then my buddy came in and told me to go puke. about 4 of us went outside and puked all over the place. the trip went straight to our heads after that and it was fantastic. never tripped that hard/weird in my life, and I've done most drugs. It was crazy, crazy fun. Some weird shit happened that we could never explain (oh wait, yes I ca - we drank Robitussin).

 

[samoth]

Fuck the DXM and candy flip 5-MeO-DiPT with some E. Or be a man and just smoke some DMT.

Actually, those frogs you lick and trip are the best.


HAHAAAAAAAAAAAAAAAAAGBGLORDF

what?

aaaaaaaaaaaaallllllliiiieeennnsss

 

[Dirk Howat]

Yah, I drank a bottle of Robotussin when I was in the army. I felt nothing for about a half and hour, then the shit hit me lit a brick. It was like being drunk and high.

 

[BrothaBill]

Alot of people talk about this brain damage that occurs with DXM use, while I dont argue that its possible, I havent seen the science to support that those conclusions can be made, In fact, the research Ive seen is its looked at as a substance that may be used to PREVENT brain damage. William White who wrote the book on how to use DXM is the one responsible for the hypothesis of brain damage, Olney's lesions, NAN. I'll say this again, Olneys lesions have never been seen in humans. If someone could give me an EXAMPLE or a CASE STUDY of this actually being observed in humans or in ANY primate, Id be very appreciative. B/c I havent been able to find it yet, seriously I would appreciate it greatly. I found alot people stating that it happens, even without evidence, so no need to send me that.
I dont want to say William White is full of shit about NAN and olney lesions.
But he is.
Even he says he believes it to be possible *his words: "in rare cases"* again completely unsubstantiated from what I have researched. Not that Im advocating longterm, frequent use.
He has alot of good info, but he's just guessing at most of it, and he wrote the DXM FAQ several years ago and has disappeared since. As I said before, he uses his own long term use experience to state what the long term use of DXM is, hardly scientific. And I suspect that William White was weird as fuck before he ever took DXM

4.15 New Medical Uses for DXM

In the past five years, research, especially research centered on NMDA receptors, has uncovered more and more medical uses for DXM. Some of these include:

4.15.1 Diagnostic Uses

Cytochrome P450-2D6, also known as CYP2D6 or debrisoquine hydroxylase, is a liver enyme which is extensively involved in metabolizing drugs. Many drugs are metabolized by P450-2D6, and many drugs also inhibit it. Some people are genetically lacking in the normal P450-2D6 variant, and physicians will use DXM to determine which variant of P450-2D6 a patient has (10-11). About 5-10% of Caucasians and 0.5% of Asians seem to lack P450-2D6 entirely, or have a very inactive mutation (12-15). In remaining individuals, its activity can vary significantly due to genetic factors (15-18). Between 0.5% and 2% of the population has multiple copies of the P450-2D6 gene and will metabolize 2D6-dependent drugs much more quickly than most people (155).

Since many drugs become toxic at high doses, it is important to give the proper amount to those people who will metabolize it differently than the normal population. DXM is used to test metabolism by CYP2D6. The patient is given a specific amount of DXM, and then the relative concentrations of DXM and its metabolites are determined.

Some recent research suggests that susceptibility to lung cancer may be related to P450 variant, and DXM may be an effective diagnostic tool for predicting lung cancer susceptibility (376).

4.15.2 Neuroprotectant Uses

One area in which DXM (as well as other NMDA blockers; see Section 10.3) shows great promise is in the prevention of brain damage resulting from excitotoxicity (over-stimulation of nerve cells to the point of cell death) and other types of nerve cell damage (19). DXM may reduce or eliminate the brain damage resulting from conditions such as fever, hypoxia (lack of oxygen) (20), ischemia (cutoff of blood to brain cells) (21-22), physical injury (23), infection (such as poliomyelitis, encephalitis, and meningitis), stroke, seizure, drug toxicity (24-25), electrical shock (231), hypoglycaemia (243), and withdrawal from long-term dependence upon certain drugs (notably alcohol, barbiturates, and benzodiazepines such as ValiumTM) (26-29).

In the case of infection (and in particular poliomyelitis), it has been demonstrated that the damage to the CNS often occurs not from the infection, but from the body's own defenses, and notably from a chemical called quinolinic acid (a metabolite of tryptophan) (30,31). Quinolinic acid is a very potent agonist (activator) at excitatory amino acid receptors, of which NMDA is one type; DXM prevents quinolinic acid from activating NMDA receptors. (Incidentally, the function of quinolinic acid - if it has any - is not currently known; it may be involved in the immune response).

As for physical trauma, hypoxia, seizure, stroke, etc., there are several experiments which indicate that the majority of the damage again comes from excitotoxicity at excitatory amino acid receptors. While DXM has shown somewhat less success there (possibly due to other factors being involved), it still has potential.

DXM is currently being evaluated as an anticonvulsant (32,33). The animal data are somewhat conflicting, but the most accurate model of epileptic seizures (called kindling) responds well to DXM. Preliminary studies in humans indicates that even very low levels of DXM may help prevent seizures. This effect is not, as was originally thought, due to NMDA receptors; instead, it is probably due to sigma receptors or voltage-gated ion channels (32).

Interestingly, DXM produces different side-effects in kindled (seizure-susceptible) animals than in non-kindled animals (this may be due to uncoupling of NMDA receptors). It is possible that humans susceptible to seizure may experience different effects from recreational DXM use.

4.15.3 DXM for Chronic Pain

DXM seems to enhance the painkilling ability of opiates without adding to the side effects, and in practice the patient can lower the dose of opiates while maintaining analgesic effect (37). As an added bonus, DXM seems to prevent opiate tolerance (see next section). DXM by itself has only marginal analgesic effect if any (373,375).

4.15.4 DXM for Drug Addiction I thnk this is the most interesting field that might come out in the future.

DXM, as well as other dissociatives, seems to prevent and even reverse tolerance to (and thus physical addiction to) many drugs. In the case of opiates, DXM has been used to treat withdrawal symptoms (169). DXM plus diazepam (ValiumTM) was tested and found to be more effective at combating the symptoms of heroin withdrawal (goose flesh, tremors, pupil dilation, joint pains, etc.) than chlorpromazine (ThorazineTM) plus diazepam (34). A further study verified this and found that adding tizanidine (an alpha-2 adrenergic agonist) to the DXM+diazepam cocktail was even more effective (133).

Dissociatives have also been found to reverse or prevent tolerance to cocaine (247), nicotine (249), and alcohol (232), and some researchers have suggested that DXM (and other NMDA antagonists) may be universally useful in most if not all drug addictions.

4.15.5 DXM for Disease and Miscellaneous Conditions

DXM is being investigated as a treatment for various diseases due mostly to its NMDA antagonist effects. The most promising results have been in treating shingles, a disease which primarily affects the elderly wherein a dormant viral infection flares up and attacks peripheral nerves. DXM can block the (often excruciating) pain from this flareup, and may prevent peripheral nerve damage (370). It may also be effective at treating herpes pain (368).

Some chronic neurodegenerative diseases may be treatable with DXM. Notable among these include ALS (Lou Gehrig's Disease) (168), although more recent research seems to show that DXM may not be a useful treatment for ALS (363). Even "Mad Cow" disease (and other prion diseases) may respond to treatment with DXM (362).

DXM has also been used to treat mental retardation (35), and Parkinson's disease (36). DXM may even have be useful in treating lung and other cancers (38) and preventing tissue rejection in transplants (263) due to the (poorly understood) effects of sigma ligands on tumor cells and the immune system (see Section 10.2).

Some papers have suggested that dissociatives have antidepressant effects (208,212,223,245,250), while others dispute this (225,229). Finally, the dissociative qualities of DXM may be of use; ketamine has been used to calm children in order to perform genital exam in cases of suspected sexual abuse (184-186).

If any one can find the science and not conjecture that DXM causes the brain damge from NAN and Olney's lesions as some believe, and that it has actually been seen in humans, or any primates for that matter. Id be very appreciated b/c I havent found it yet.

Aliens and other higher beings on higher plateaus are very common among user's trip reports at higher plateau doses. Who am I to say they didnt experience them as they believed, just passing that info. on from numerous user trip reports. I can provide sources for those who dont believe that Im being candid with that fact as it is well documented. The users used the term "aliens", I suspect as it is near impossible to explain those experiences that was the best word they could come up with to describe what they felt. Take it as you wish.
Research on DMT from the fifties also shows that to be a very common experience as well, Im not making it up. One only needs to read the science literature on the users reports to determine that Im not BSing about that.
Licking the frogs from South America, besides not finding a ready source of frogs. The substance is 5-meo-dmt which is not DMT as some people think. Just b/c dmt appears in the name does not mean that it is, in fact DMT. And honestly, despite what some say here, DMT is never for recreational use.

Everything in life is a trade-off, drugs often take with one hand as they give with another. If you choose(as it is your choice) to use this, then go through the experience and then reflect on the doors it may have opened up for you while you are not altered.

While some may get pissy about discussing DXM and discussing the safest way of using it, Id rather see a thousand people take DXM rather than one person chug a bottle of Nyquil and die.

 

[samoth]

I was waiting for you to bump this back up.

And contrary to popular belief, some of us do have a source for south american licking-frogs, thankyouverymuch.

We just gotta find a better way of getting past customs, as they get somewhat suspicious when they come across a box with breathing holes poked in it.

 

[BrothaBill]

I was waiting for you to bump this back up.

And contrary to popular belief, some of us do have a source for south american licking-frogs, thankyouverymuch.

We just gotta find a better way of getting past customs, as they get somewhat suspicious when they come across a box with breathing holes poked in it.

I you Samoth, I knew you were going to come and make fun of this at some point, I had to jab back a lil at ya.

Why frogs anyhow, when you can grow your dmt laden grass no probs in the US and extract it rather simply. Smoke a lil DMT and VRROOOOOOOOMMMMM~~