I asked the following question at anabolicextreme.com, a board whose members I much respect, but I do not know what to make of the answer, as I have heard many conflicting viewpoints. What do you think?
QUESTION: The advice that other vets have given me is NOT to take before bedtime, as you will blunt the release of you natural GH by doing this. What are your thoughts?
ANSWER: Some of the most widely regarded, and experienced, Hormone Replacement Therapy physicians direct that hGH be used at bedtime. They see this time of administration as enhancing the effect of hGH, rather than diminishing it. Another recommended time of administration is immediately upon waking up in the morning. It has been shown that there is a natural spike in natural hGH production, then, and, again, it is felt that exogenous administration, at this time, enhances it.
Serostim product insert literature, itself, recommends bedtime administration of hGH.
In my own use, as well as with my clients who have used hGH, under my direction, I have found no diminution of effect for hGH, administered at bedtime and/or waking up in the morning, compared to it's use at other times. Bedtime usage of hGH is convenient for many users, so I have no trouble at all, in recommending it.
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THIS same vet, Muscletrainee, whom I have nothing but the utmost respect for, suggests dosing of GH one hour post meal, with an hour before your next meal.
So I asked the following, and he answered. What do you think of this? I ask because I do not understand his line of thought.
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QUESTION: the basis of this line of thought?
ANSWER: I suggest you read this thread:
http://forum.anabolicextreme.com/viewtopic.php?p=18548&highlight=#18548
I will, however, cite the most applicable paragraph of the thread, with the key sentence in all caps:
"I had my first ever blood work done back in 1998 when it was discovered that my test level was low (below 200). I was referred to an endocrinologist and was put on HRT after a battery of tests. This process took about a year before I was actually given HRT. I was using prohormones at the time and the endo had me go off that and would periodically retest me to see if there were any change. I was given an MRI of the brain to check the pituitary. The most intensive test I had was an insulin/hypogycemic test in which I was attended to by a doctor and two nurses in a hospital. They would shoot insulin in one arm vein and when I was about to pass out they would shoot glucose into the other arm. The whole test lasted about 3 hours. When looking at some of the test results I noticed an inverse relationship between low blood sugar and GH. When blood sugar was low GH spiked and after they would pump some glucose into my vein GH would drop dramatically. THIS WOULD LEAD ME TO BELIEVE THAT IF YOU SELF-ADMINSTER GH YOU SHOULD DO SO ON AN EMPTY STOMACH AND DON'T DRINK CARBS DURING HIGH INTENSITY TRAINING."