I cant quote specifics off the top of my head, but many of the strongest and biggest guys in the world, as well as some clinical studies, will argue that staying with lower reps will be more effective for hypertrophy as well as additional benefits of increasing bone mass as well as tendon and ligament strength and overall joint stability because by using heavy weight (weather using short rest periods or long) your body is continually subjected to extremes with which your body will adapt to. Many also claim that lower reps are safer because of decreased set duration means concentration levels are higher.