stanzolic

[tholdren]

Yes, theride, you do get less of the drug with oral administration.

This is due to the "first pass effect", which means that everything you eat (pills, food etc.) goes directly to the liver before reaching any other part of the body.

This is to your benefit in that your liver detoxifies things before they can reach the body's more sensitive tissues.

By injecting intramuscularly, you bypass the liver's powerful action and get more of the drug to your muscles than if you took the same dose by the oral route. The liver degrades the drug at a much slower rate, because the drug is coming from the muscle you injected, not the gastrointestinal tract.

Just look up "first pass metabolism" on Google and you will see the benefits of parenteral, or injectable drugs as opposed to oral administration.

 

[androjunkie]

Blood in your urine? kidney pain???? I'm not sure if I would attribute that to winstrol esp. if you taking it at sane dosages or heavy lifting... have you thought about going to the dr.?

Don't worry everybody, it wasn't from the winny. It was just because I was able to lift more than I ever could before and the weight caused small ruptures in my ureter's. I took some time off the gym and it all got better.

 

[guards]

Fisty? FISTY? where did you go?

i thought you knew everything...hello?

 

[fisty]

hey guards guards I'm right here....I takes more to make me leave then that bro......any way.....I still can not see how 50mg shot is the same as a 5mg pill.......call me a dumbass/moron/and what ever else you want...to me it makes no sence at all.....

 

[guards]

hey guards guards I'm right here....I takes more to make me leave then that bro......any way.....I still can not see how 50mg shot is the same as a 5mg pill.......call me a dumbass/moron/and what ever else you want...to me it makes no sence at all.....

dude, a 50mg shot is NOT the same as a pill. I totally agree with you on that. But if you were to take a 50mg shot a day versus 50mg of winny pills a day, the result should, in theory, be the exact same. Orally you might lose a little bit of the drug but essentially the effects will be identical.

 

[fisty]

yes I understand that.....totally....but my question was if the life of a pill is about what 4-5 hours untill you have to take your next pill, and the life a 50mg shot is 48 hours then I inturn have some point here. yes If I took just 50mg by a shot then I would shoot everyday or everyother day....granted now if I took a shot every other day, and took some pills the days between, yes I would have more winny in my system...but wouldn't that make more difrence in my whole cycle??? not just because there is more in the system but because there are two seperate lifes that I will be working with now??? (pills=shorter) (shot=longer)

 

[guards]

yes I understand that.....totally....but my question was if the life of a pill is about what 4-5 hours untill you have to take your next pill, and the life a 50mg shot is 48 hours then I inturn have some point here. yes If I took just 50mg by a shot then I would shoot everyday or everyother day....granted now if I took a shot every other day, and took some pills the days between, yes I would have more winny in my system...but wouldn't that make more difrence in my whole cycle??? not just because there is more in the system but because there are two seperate lifes that I will be working with now??? (pills=shorter) (shot=longer)

K, i think you are getting a little confused. If your body has an amount of any substance, lets call it X, then substance x get dissolved at a certain rate which is called the half-life or the time required for your body to use half-the drug. Now, if you continue to add substance X, regardless of method of administration, you will just keep getting more of the substance in your body. If you take a shot of 50mg of X EOD or you take 25mg in pill form ED, the rate at which your body uses this susbtance will remain constant. The wrench in the equation is the amount of drug X that is absorbed by your body. It is true that an injection will absorb more drug, albeit not a substantial amount, effeciently than an oral administation. There are NOT two separate half-lives to the same compound.

 

[tholdren]

Fisty,

It is obvious that you have learnt nothing regarding drug metabolism from Guards or me. Your continued reference to the "life" of a shot etc. demonstrates this nicely.

Take your IM Winstrol and the oral pills if it makes you feel better.

Do us a favor and make sure that you have regular blood work done (liver function tests and lipid profile) because you will be doing more Winstrol than is normally done and you should make sure you are not harming yourself with the increased dosage.

Go to the internet and research "oral versus parenteral drug administration", as well as "drug half-life" and feel the satisfaction of having completed some self-directed learning.