javaguru
Banned
I think it's fair to conclude that sooner is better than later. Although the study didn't find a statistcally significant difference between one hour and three you are still reversing the negative protein balance caused by an intense workout and restoring muscle glycogen as soon as possible. Blunting protein degradation is also a reason I use a workout shake. I typically advise people to have a shake immediately post workout and then a "normal" bodybulding meal an hour later. In this way you're taking full advanatge of your post workout window and it allows time for the food from the second meal to digest. I've found this protocol imperative if you're going to train intensely five or six days a week.
Lifterforlife said:Ok, here is the study you cited....seems some discrepency in the 1 hr. window. Kind of a leap saying only one hour when the study cites one or 3 hr. Hardly a definitive study to base a whole protocol of 1 hr. window.
Read similar anabolic responses at 1 or 3 h
Not to mention the study was done with all of 6 people, hardly quantifiable evidence.
J Appl Physiol 88: 386-392, 2000;
PubMed
PubMed Citation
Articles by Rasmussen, B. B.
Articles by Wolfe, R. R.
Vol. 88, Issue 2, 386-392, February 2000
An oral essential amino acid-carbohydrate supplement enhances muscle protein anabolism after resistance exercise
Blake B. Rasmussen, Kevin D. Tipton, Sharon L. Miller, Steven E. Wolf, and Robert R. Wolfe
Department of Surgery, University of Texas Medical Branch and Metabolism Unit, Shriners Burns Institute, Galveston, Texas 77550
This study was designed to determine the response of muscle protein to the bolus ingestion of a drink containing essential amino acids and carbohydrate after resistance exercise. Six subjects (3 men, 3 women) randomly consumed a treatment drink (6 g essential amino acids, 35 g sucrose) or a flavored placebo drink 1 h or 3 h after a bout of resistance exercise on two separate occasions. We used a three-compartment model for determination of leg muscle protein kinetics. The model involves the infusion of ring-2H5-phenylalanine, femoral arterial and venous blood sampling, and muscle biopsies. Phenylalanine net balance and muscle protein synthesis were significantly increased above the predrink and corresponding placebo value (P < 0.05) when the drink was taken 1 or 3 h after exercise but not when the placebo was ingested at 1 or 3 h. The response to the amino acid-carbohydrate drink produced similar anabolic responses at 1 and 3 h. Muscle protein breakdown did not change in response to the drink. We conclude that essential amino acids with carbohydrates stimulate muscle protein anabolism by increasing muscle protein synthesis when ingested 1 or 3 h after resistance exercise.
muscle protein synthesis; stable isotopes; nutritional supplementation