I say do WHOLE BODY workouts every day.
Like the 5x5: squat, bench, row / front squat, standing press, chins
or oly lifts and strength: snatch, squat, dip / clean, press, snatch-grip dead / jerk, front squat, pend row
rarely go to failure, and alternate lighter days/exercises with higher intensity.
For example, maybe have a workout with a very stressful squat session which leave your legs sore and you just run through the motions on the bench and row, then the next day/workout, do a moderate weight for squatting, and then beat the crap out of your chest and lats.
Idea behind this is:
You can hit the whole body 3-5 times a week without overtraining - as opposed to just once a week if you're doing a normal split where you do say 5 leg exercises and are then super sore for 3-5 days. This means you build up 150-250 workouts for each muscle group a year as opposed to just 50. In the workouts where you use a moderate weight, you can work on form and flush the muscle with blood (and nutrients) and develop the neuromuscular skill and flexibility. You heal up faster and increase metabolism with daily whole body workouts.
Take of days when you feel blown out or just do 20mins cardio and stretching to promote healing.