I just realized something about 1-AD

[Lumberg]

It makes me really, really tired.

I took 200 mg about 2 hours ago on a full stomach and I can barely keep my eyes open. I have noticed this before as well. I got 9+ hours of sleep last night so there is no reason to be tired except for this.

Anyone else notice this?

JC

 

[SlapItHard]

Ive been on it for about 18 days so far at 600mg a day, it hasn't made me tired yet. Are you stacking with anything else?
'

 

[Dante B.]

It was assumed, Estrogen, decreased by 1AD/1-Test was the culprit in this malady of well being, but, for such the effect to come upon you so fast likely does this (perhaps) prove that alterations of brain chemistry are the cause (and not Estrogen alone).

 

[Lumberg]

No. I'm not stacking.

And I wouldn't call it a decrease in well being. I feel ok, just sleepy.

I was stacking with andro 400 mg/day but the immediate accumulation of water (and maybe a little fat) was just too much for me. I think it was because since I already had high androgen levels that my body was converting virtually all the andro to estrogen. I would never do andro again without arimidex.

I'm looking into the relative costs of andro plus arimidex vs. 4-AD since andro is so cheap.

JC

 

[pa1ad]

It was assumed, Estrogen, decreased by 1AD/1-Test was the culprit in this malady of well being, but, for such the effect to come upon you so fast likely does this (perhaps) prove that alterations of brain chemistry are the cause (and not Estrogen alone).

I am not so sure its lack of estrogen. Some other non aromatizing androgens do not have this effect. Halotestin seems to though. DHT and its derivatives certainly don't

 

[Lumberg]

I think that I might split up my doses so I take my big dose (200 mg) at bedtime to take advantage of these effects.

Pat, let me ask you again:

At 400 mg/day, what is the optimal dosing sequence? 100-100-100-100 every few hours, or 100-200-100 or 100-100-200 evenly spaced? If the 200 was in the middle of the day it would come immediately post-workout.

Also, do you have any more reliable oral bioavailability figures (the only one I know is an estimate of 30% by Big Cat). Am I correct in assuming it is at least 15% as with the other diols?

JC

 

[Scaggs]

Joncrane, any other sides noticed yet? I've heard about the tiredness from 1-ad. You're not the only one. The 4-ad really made you hold that much water huh? I should take that. What make is it?

Scaggs

 

[Lumberg]

It wasn't 4AD. It was regular androsteneDIONE. (4AD is androsteneDIOL.) Unlike 4AD, it can covert directly to E.

Other than tiredness, I THINK (not sure because I don't pay too close attention) I notice a little more hair growth on my arms (shich I shave anyway) and a few more blemishes/pimples on my skin.

I do NOT notice any lack of libido whatsoever--I get hard-ons all the time.
If anything my libido might be a little higher, but that perception may be because I am looking at porn almost every night just to see if my libido is still there

JC

 

[pa1ad]

I think that I might split up my doses so I take my big dose (200 mg) at bedtime to take advantage of these effects.

Pat, let me ask you again:

At 400 mg/day, what is the optimal dosing sequence? 100-100-100-100 every few hours, or 100-200-100 or 100-100-200 evenly spaced? If the 200 was in the middle of the day it would come immediately post-workout.

Also, do you have any more reliable oral bioavailability figures (the only one I know is an estimate of 30% by Big Cat). Am I correct in assuming it is at least 15% as with the other diols?

JC

200, 100, 100, 100

or

200, 200


I have no idea what oral bioavailability is. Big Cat pulled those numbers out of his ass

 

[Lumberg]

200, 100, 100, 100

or

200, 200


I have no idea what oral bioavailability is. Big Cat pulled those numbers out of his ass

I hear ya.

The first dosing sequence adds up to 500. Are you saying I should definitely hit with 200 mg in the a.m. and then either go 100-100 or 200 pre-bed?

If so I will go 200-200 to take advantage of the sleepiness at night.

JC