Virilization:
This term refers to the possible masculinization that females may sustain due to the ingestion of anabolic/androgenic steroids. As in male athletes, steroids also cause a suppression of the gonad cycle in females. The hypophysial excretion of HDL and FSH is inhibited which results in a secondary amenorrhea, meaning absence or abnormal cessation of the mensis. This side effect is reversible after the steroid has been discontinued. Visible signs of a virilization can be acne vulgaris (simple acne), hirsutism (excessive bodily and facial hair), alopecia (androgen-induced loss of hair), and changes of the skin structure similar to the males'. These side effects are usually considered reversible but, depending on predisposition or with the consumption of high dosages of mostly androgenic steroids and with extended usage, there is a possibility that these changes may remain after the steroid has been discontinued. The same is to be said about a possible clitorihypertrophy. The first sign of virilization is often a slight change in the voice in form of hoarseness. A deepening of the voice is irreversible and usually remains life long. in women one must also take a possible increase in the libido into account. Some females become increasingly aggressive during steroid intake only to fall into a depressive state after steroids are discontinued. The increased aggressiveness is due to the elevated androgen level, whereas the possible depression is suggestive of an estrogen rebound which occurs after the steroid regime has been discontinued. Since the estrogen production is suppressed by the LH and FSH inhibition, a significant elevation in production can follow. If steroids are taken during pregnancy, there is the possibility of a masculinization of the female fetus. The occurrence and manifestation of these side effects depends largely on genetic factors, the dosages, the length of consumption, and the type of steroids given. In spite of all the known excellent, performance-enhancing effects of anabolic/androgenic steroids in female athletes, one must weigh the risk against the gain, since many of the potential side effects are not reversible.