a little over 3 weeks on letro and still not doing all that much for me. I feel like the puffiness is getting worse and i get shooting pains in my nips randomly. The pill form I usually felt it within 4-5 days and had 0 gyno symptoms within 2 weeks, not sure whats going on with this stuff tho. hope it pulls thru as i have one more week left of it before i switch to aromasin