I've just finished a run of 2 bottles of 6-OXO and also believe that it works to lower estrogen, although a little pricey. I'ved been experimenting with otc supps just to see how my body reacts. I have been slightly amazed by the strength increases that I'm getting from 1AD, 1-Test and 4-Test in combonation with a very good diet and a pretty good training program. I'm looking big and full.