The P7 Journal

[Fonz]

Ok, this latter experiment is to test out 6-oxo-DHEA's effect on mood and immune function.

Stats: 193lbs at 11% 5"9

I have been on Fina for 40 weeks.

Blood test results after 21 weeks of Fina w/ thyroid panels and kidney panels:

I had also been using T3 for 16 weeks in low
doses. 12.5-25mcg/day (Weeks 1-16)

AST(SGOT) 72 Normal Range: 2-50

ALT(SGPT) 78 Normal Range: 2-60

ALK(Phos) 59 Normal Range: 20-125

Albumin: 5.2 Normal Range: 3.7 - 5.1

T4, Total: 5.0 Range: 4.5-12.5

T3, up-take: 47% Normal: 27.8-40.7

T4, Free(Calculated): 2.4 Normal: 1.6-3.7

T4, Free(Non-dyalisis): 2.1 Normal: 0.8-1.5

TSH: 1.8 Normal 0.4-5.5


Well......my liver enzymes are slighlty elevated,
and my TSH is a tad low(I was on T3 so that was expected), but all in all Ok.

BUN: 19 Normal: 7-25

Creatinine: 1.3 Normal: 0.5-1.4

BUN/Cr Ratio: 14.6 Normal: 6-25

Kidney function was well within specs.


I am currently on:

1. 100mg Fina/day
2. 1ml P7 dropper/day divided in PM and AM
3. Sodium Usniate: 800mg/day
4. Bromocripine: 1.25mgs/day
5. Yohimbine HCL: 20mgs/day
6. EQ: 400mgs/week
7. r-ala: 1000mgs/day
8. Tyler Liver Detox: 4 caps/day
9. NYC: 4 caps/day
10- Garlic(Aillicin): 12800mcgs/day
11. 50mcgs T3/day

The other main purpose of this study is to determine garlics effects on my HDL/LDL and P7's effects on my immune system/mood.

My HDl:LDL ratio was 12:120 btw or 1:10...not excatly stellar.

Day 1: Nothing to report
Day 2: Nothing to report

Note: I really do like the smell though...

Day 3:

I normally don't sleep very well b/c of the Fina induced warmth, but last night I didn't toss and turn as much.
Also, I actually woke up slightly energetic, which is rare for me. I need a t least 2 cups of cofee to start me going.
I also am pretty irritable in the mornings, but today I actually didn't scream at the cofee machine for once.

Day 4:

Fonz

 

[Fonz]

Day 8 Report:

Nothing special yet. Mood is calm as always. Probably b/c I don't run test w/ Fina.
I did however find something very interesting.

Now P7(6-oxo-DHEA) is reputed to help sleep.
Well, in my case..barely.(Could also be placebo)

However, add 6mg Melatonin and BINGO, ladies and gentlemen we have a winner..
I slept like a log for 9 hours.
And melatonin does NOTHING for me. I've gones as high as 20mg and it didn't do a thing. I just wanted to use the
2 120's bottles i bought a month or two ago at the vitamin shoppe. I Still have 50 3mg tasb left so might as well use them.

So I'm doing th P7(3/4 pippete) + melatonin(6mg) thing tonight again, b/c I fely really, really good this morning.

Oh, And bodyweight today(AM): 189lbs

Fonz

 

[Fonz]

Day 6 Report:

Note: Thi is Day 6 not 9. I must have been delirious from studying too much before.


Nothing special yet. Mood is calm as always. Probably b/c I don't run test w/ Fina.
I did however find something very interesting.

Now P7(6-oxo-DHEA) is reputed to help sleep.
Well, in my case..barely.(Could also be placebo)

However, add 6mg Melatonin and BINGO, ladies and gentlemen we have a winner..
I slept like a log for 9 hours.
And melatonin does NOTHING for me. I've gones as high as 20mg and it didn't do a thing. I just wanted to use the
2 120's bottles i bought a month or two ago at the vitamin shoppe. I Still have 50 3mg tasb left so might as well use them.

So I'm doing th P7(3/4 pippete) + melatonin(6mg) thing tonight again, b/c I fely really, really good this morning.

Oh, And bodyweight today(AM): 189lbs

Fonz

Day 9:

Nothing to add today:

200mg Fina
Kicked up my yohimbine HCL dosage to 30mg/day
NYC still at 4 caps/day
1.25mgs Bromo
P7 1/2 dropper AM
P7 1 dropper PM w/ 6mg melatonin

No change in mood whatsoever.

But again, slept like a log w/ the added melatonin(6mg).

I'm going to try to find out how 6-oxo-DHEA interacts with melatonin for improved sleep.

I find it curious 6-oxo-DHEA is just very mild. Doesn't do much for me in terms of mood, but when combined with melatonin, its like ambien for sleep(Which is a godsend for me).
Good sleep too. Even after injecting 200mg Fina this AM.

Fonz

 

[Fonz]

From AFWritten by me)

Possibilities I can think of how P7 works:

Increased bio-availibility of T4 and conversion to T3. T4 has a MARKED effect on mood. I proved this at CEM.
Since 6-oxo-DHEA, doesn't convert then...nothing there.
It HAS to be the pregnenolone..just has to be.

And I'll be the farm its due to too much/to little dopamine latching onto the receptors.

GHB increases Dopamine(and to a smaller extent blocks the re-uptake).

P7 just does it to a SMALLER degree.

Ok, I think I got it know.....

P7 dosaging has to be standardized for the person. It just does. Or it won't work well for them.

If not enough P7 is taken, not enough dopamine latches onto the receptors and you get no results.

Too much P7, and you get TOO MUCH dopamine latching onto its receptors and bingo, you get a headache...exactly the same happens with Bromo.(I'll bet $100 this has happenned to people)(Bromo is also a dopamine agonist)

Now, if you hit the dosage right on, you should get a calming effect because JUST enough dopamine is latching onto the receptors and enough is left in circulation, for you not to get all hazy like you wpould do with GHB.

The trick is to get the dosage right on.

I'm going to try it at 1 pipette instead of 1/2 pipette 2x/day...AM and PM.

And we shall see.

Fonz

 

[Fonz]

Up-date:

Do not take Bromo or any other Dopamine agonists while on P7.
They will block the effects of the P7, since the latter works on the PNS(Para Sympathetic Nervous system) and has an effect on dopamine. Which is what induces the "calmness feeling".

Fonz

 

[Fonz]

Day 10:

Started DMAE + P7.
DAME is a weak enough dopamine agonist and does not interfere with the P7(6-oxo-DHEA and the pregnenolone) as Bromocriptine(which is a much more powerful Dopamine agonist).

Not much yet, but the Bromo has not cleared my system yet.....I'll give it a day.

Fonz

 

[Fonz]

Slept like a damn log today.

1ml P7 + 260mg DMAE.....

14hrs of sleep.

Damn, I feel good. Bromo is to strong and overrides the Dopaminergic blocking effects of the P7. Not so DMAE.
Its weak enough to let P7 do its job.

Fonz

 

[Fonz]

My conclusions on P7:

This is what i thought of P7. The Pros and Cons surrounding it.
First off, MORE is NOT BETTER.

I hope this is all understood b/c I learned it the hard way.

I use a lot of Fina.....and I get a pimple every now and then.

And no offense to anybody else, P7 makes you break out like crazy(If your dosage is wrong).

Make a 6-oxo-DHEA version WITHOUT the pregnenolone. Which is the culprit for sure. And then I'lll buy it again b/c I like higher dosings. And it can be used exclusively by people who use it post-T3 cycle or during Clen or NYC/ECA stacks.(And some other people who have certain diseases and don't like oily skin, but thats another story)

I had to stop the P7 b/c of the break-outs.

Never had them in my life.

Other than that, I have no problems with the P7.

I definately helped me with sleep during Fina and thats something that was VERY surprising to me.

Also,

As i told Ulter before macro, its the DHEA analogue that produces the raised T3 levels.

Pregnelone's effects on mood is a dicey subject. Could be a placebo effect and we all should accept this as a possibility.

I think P7 is better for older people(30+) and those coming off a T3 cycle.(P7 will help in thyroid recovery and mood)

As I have said before, START VERY LOW.

Like 1/8th pipette low......then work your way up.

Or you will break out. I can almost guarantee it.

Bozo-brained me started at 1/2 pipette and paid the price for the stupidity. I got oily skin in a big way.

Fonz