If your thinking about doing eq start at around 400mg... imo there is no reason in starting out at a higher dose. If you have problems with anxiety start at a lower dose if your concerned. The only time I had issues with the anxiety was when I would wake up suddenly or forget that I shouldn't take jack3d lol. There were a few times when I had a long day so I felt a little jack3d was needed, I felt anxiety for a few days before I remembered it was probably the combination of eq and the jack3d.
Other than that I think you will love the stuff. I couldn't run because my lungs and body hurt and after doing the eq I was able to run 3 miles without stopping. I'm off going on 2 months now and I still thank the eq for giving me the strength to run. It's not as easy without the extra rbc but I can still do it!