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napsgear
genezapharmateuticals
domestic-supply
puritysourcelabs
Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

Testicular cancer survivors and AAS? Beginners cycle review

@labtec70 - Thank you sincerely for a very informative post.

Do you get any symptoms of low testosterone?
Low Libido, night sweats, lethargy, depression, no morning woodies or few sexual thoughts, impotence, increased fat gain and/or decreased muscularity, poor concentration and mental clarity?
*Lethargy - yes *Depression - Yes *Few sexual thoughts - Yes *Impotence - slight change in strength and duration..

Guess I should continue working on my diet, train hard, and get my T-levels, liver enzymes, respiratory/renal functions - checked before I go any further.......

Thanx goes out to all whom contributed thus far. Anyone else who would like to share anything or ask questions, please feel free.
 
Hi Plat

You really do need to get your hormone levels checked if you've got some symptoms.
Secondly, I think I got it wrong...Bleomycin is the one that can affect lung function, but really most guys do okay unless you are a cardio/endurance athlete or cyclist. Still, better get it checked by your GP to get a handle on it befoe going hardcore in the gym.
 
Wow man unbelievable you had and survived cancer at our age (I'm 26 as well) Congratulations!

I have had a few medical issues setting me back from bulking up as much as I'd like - and I would love to run gear. Unfortunately no one with a decent rep has suggested such, just work on diet and training :P I'm 5'10 175 9% BF.

Someone mentioned that estrogen can contribute to cancer - but not test, yet test will aromatize to estrogen so I'm unsure as to this statement.

I have run some natural test boosters with good luck though, Testrol being one. DAA helped (I think, at least my GF said it did).

Have you looked into peptides? That's been what's keeping me up late at nights with my eyes glued to the computer screen researching.
 
I use heavily and pass all my cancer screens. I have to be checked 2x/year since my cancer cleared. Just avoid orals or tren near your test.
 
@ lovesnatches - Thanx man! Appreciate it!

Yeah it's kinda tough to find decent help regarding juice. Most of the doctors here interrupt me mid-sentence with "DON'T USE IT!!, as soon I as mention the words "anabolics" or "steroids". Yet, at my local gym, I see firsthand how guys aged +-20 buy some Dbols, a vial of Sustaplex, and off they go. 70% of them have no idea what PCT even is. This one guy went on to win an amatuer bodybuilding contest after one of such cycle (he gained 8kg consuming 4500 cals/day). Get this...NO PCT whatsoever. The sides he mentioned : acne, increased sex-drive (really??) and testicular atrophy. Somehow he isn't worried too much because "more experienced" juicers at the gym said don't worry, they will become their normal size real soon! I simply went WTF.

As far as I know the only cancer and estrogen link is with breast cancer. Testosterone and cancer are in turn linked with prostate cancer. But the studies I've found on that too, are pretty mixed :

Higher serum free testosterone is associated with an increased risk of prostate cancer: results from the Baltimore longitudinal study on aging. J. Kellogg Parsons, H. Ballentine Carter, Patricia Landis, E. James Wright, Elizabeth Platz, E. Jeffrey Metter.
--and--
No causal relationship found between testosterone replacement therapy and prostate cancer or heart disease risk. A retrospective analysis by researchers at Beth Israel Deaconess Medical Center (BIDMC) published in The New England Journal of Medicine
Guess the TRT sections will shed more light on this.

Regarding natural test boosters : I've tried herbal ones like ZMA, Tribulus, Testoblast, etc. Didn't really see or feel any big difference. Marginal strength gains(placebo effect?) and better sleep..
In my current situation I wouldn't opt for something like that even if it worked really well. Just don't want to put too much strain on the only remaining trooper by forcing it to make more test.

What about these peptides you mentioned? Can you give me a good link or something?
 
@ Pound4PoundAAS - "I use heavily and pass all my cancer screens. I have to be checked 2x/year since my cancer cleared. Just avoid orals or tren near your test"

Finally a fellow survivor! Congrats bro! Few Questions... What type of cancer? What kind of treatment? How old when diagnosed/cleared? What gear are you running/doses?

Would love to get some feedback.
 
Yeah I thought about ditching the laziness so I googled peptides... Very interesting! Further reading showed a connection between cancer growth and Human Growth Hormone.... Man, how I HATE that C-word....

Thought I'd share what I found:
We all know the benefits of Growth Hormone from a bodybuilding standpoint. Basically it does what the name says, it makes you grow. There are many different mechanism as to how it accomplish this[increasing protein synthesis capabilities, increasing the amount of insulin a person can use effectively, and the release of Insulin-like Growth Factor (IGF-1) which increases cell-division and even creates new muscle cells, hailed as the "Rolls-Royce of muscle building hormones"] Problem comes in when an imbalance is created. Anytime insulin to glucose, testosterone to estrogen, HGH to IGF-1, or any other ratio gets out of balance in human physiology, illness seems to happen. It's only natural. When it comes to cancer, a high level of insulin-like growth factor-1 (IGF-1) appears to be the culprit when IGF-1 : HGH ratios are out of whack.

When I continued reading it seemed that this wasn't really the case. Research show that robust levels of HGH just may prevent many cancers. The problem as mentioned above is mainly IGF-1. But why? The problem lies not with IGF-1 as a stand-alone hormone, but in the IGF binding protein-3 (IGFBP-3), better stated: the lack thereof. When THIS ratio of IGF-1 : IGFBP-3 is upset, the shit could hit the fan:

Researchers announced that, in a six-year study of 32,826 nurses, those with the highest levels of IGF-1 had a two-and- a-half times greater risk of colorectal cancer.
------on the flipside-------
High levels of IGF binding protein-3 (IGFBP-3) produced the opposite effect. Taken from the Department of Nutrition at the Harvard School of Public Health

In the case of those with the highest IGF-1 and lowest IGFBP-3, the relative risk of colorectal cancer rose fourfold, after accounting for differences in weight, height, alcohol intake, and other known risk factors. OK so what do we know now? Let's recap. An increase of Human growth hormone leads to an increase of IGF-1. When IGF-1 levels are increased so much that its ratio to one of it's binding proteins: IGF binding protein-3 (IGFBP-3) become too big, cancer risks increase. Almost all (>95%) of serum IGF-1 circulates bound to specific IGF binding proteins (IGFBPs), of which six classes (IGFBPs 1-6) have been identified. BP3 is thought to be the major binding protein.

Now we have to look at the peptide itself, available for purchase for use in bodybuilding. I'ts called - IGF-1 LR3
The goal when injecting the peptide is to skip the part being precursed and released due to the release of Human Growth Hormone, and to be made readily available for use by the body. This is how its done : “Long R3 IGF-1 is signifacantly more potent than IGF-1. The enhanced potency is due to the decreased binding of Long R3 IGF-1 to all known IGF binding proteins. These binding proteins normally inhibit the biological actions of IGF’s.”

So they purposefully made it to be bound less by IGF binding protein-3 (IGFBP-3)? Didn't we just see that when this ratio of IGF-1:IGFBP-3 is disrupted it creates a high-risk cancer environment as the studies above prove?

I might be missing some serious point here on the workings of IGF-1 LR3 and its binding proteins, or it looks seriously dangerous.

Can someone call a peptide-guy?
 
Hmm my local supp shop is owned by a pro and he was uncertain with the Ghrps as well because of the lack of research. He uses hgh I'm sure.

Damn that c word changes everything with this. Anything exogenous could theoretically cause cancer. You are good at your research I'm a little jealous even with a BS in psych.
 
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