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Reduced Glycemic Index and Glycemic Load Diets Do Not Increase the Effects of Energy Restriction on Weight Loss and Insulin Sensitivity in Obese Men and Women -- Raatz et al. 135 (10): 2387 -- Journal of Nutrition
Weight loss and insulin sensitivity improved with weight reduction similarly in all 3 groups. Although insulin sensitivity differed between the LGI and HF diets at wk 12, none of the groups differed at wk 36. The amount of weight loss predicted by energy restriction was achieved under controlled dietary conditions. However, the reduced glycemic index and glycemic load did not demonstrably enhance weight reduction in obese men and women.
Upon completion of the feeding phase, subjects in the LGI and HF diet groups tended to have a reduction in body fat and maintenance of lean body mass loss. Our results are consistent with those of Boucher and colleagues (15) who demonstrated lower fat mass by densitometry in subjects following a low glycemic index diet. However, at the conclusion of the free-living phase, body composition did not differ among the groups. It is noteworthy that participants successfully maintained weight loss in a free-living environment when provided with intensive education, consistent nutritional support, and regular follow-up.
The results of this dietary trial demonstrate that energy restriction over a 36-wk period promotes weight loss and improves insulin sensitivity in obese individuals, irrespective of dietary substrate. The hypothesis that a low glycemic load diet would enhance weight loss, relative to other diets, was not supported in either study phase. However, the LGI diet did improve insulin sensitivity at 12 wk compared with the HF diet.
Weight loss and insulin sensitivity improved with weight reduction similarly in all 3 groups. Although insulin sensitivity differed between the LGI and HF diets at wk 12, none of the groups differed at wk 36. The amount of weight loss predicted by energy restriction was achieved under controlled dietary conditions. However, the reduced glycemic index and glycemic load did not demonstrably enhance weight reduction in obese men and women.
Upon completion of the feeding phase, subjects in the LGI and HF diet groups tended to have a reduction in body fat and maintenance of lean body mass loss. Our results are consistent with those of Boucher and colleagues (15) who demonstrated lower fat mass by densitometry in subjects following a low glycemic index diet. However, at the conclusion of the free-living phase, body composition did not differ among the groups. It is noteworthy that participants successfully maintained weight loss in a free-living environment when provided with intensive education, consistent nutritional support, and regular follow-up.
The results of this dietary trial demonstrate that energy restriction over a 36-wk period promotes weight loss and improves insulin sensitivity in obese individuals, irrespective of dietary substrate. The hypothesis that a low glycemic load diet would enhance weight loss, relative to other diets, was not supported in either study phase. However, the LGI diet did improve insulin sensitivity at 12 wk compared with the HF diet.