No it works as an uncoupler much closer to DNP in that way. It works on the PPAR which is the receptor that controls fat and sugar metabolism. Here's an explanation.
How does Sesamin increase fat loss?
Sesamin and episesamin are chemicals that strongly activate PPAR-alpha, and increase mitochondrial and peroxisome activity. Basically this increases fatty acid metabolism significantly. Also, Sesamin increases the expression of a mitochondrial enzyme known as carnitine palmitoyl transferase. Carnitine palmitoyl tranferase is an enyme that shuttles fatty acids to the mitochondria, making more fatty acids available for use as energy. When you take Sesamin it can be like putting your fat on a one-way bus to the fat furnace. To top it off Sesamins activation of PPAR-alpha increases the production of "uncoupling proteins" (UCP's). Uncoupling proteins are kind of like DNP, except legal and safe. The amount of UCP's that you produce is one of the main factors in what your basal metabolism is. Electrons are transferred in the inner membrane of the mitochondria, and produce ATP in exchange . When this electron transport chain is "uncoupled" you burn energy (mostly fat) oxidatively (with oxygen), at an accelerated rate. So basically Sesamin and episesamin shift your metabolism considerably more in favor of utilizing fat, instead of storing it.