Hard to say what's working the best but I'm on sesapure, trex, cardiobreeze, alcar, altar, plus glucorell before meals with carbs and I'm down from ~245lbs to ~220lbs in a little over a month. I was thinking it could be water weight but I tried getting back in the gym last year for about a month without all these supps and NEVER lost this much weight.
Strength is also through the roof starting this week for some reason. Not near what I was 4 years ago which was the last time I have been in the gym for more than a month but definitely much stronger than a few weeks ago