I have to do this....................
Also do a search on the site, there is someone using it right now, this is a post I made on his thread.........
I found this post by another molecular endocrinologist I know....................
Don't buy stock in dnp - dinitrophenol - . We are about to put it down on the popularity list.
It fucks very badly indeed, with a whole slew of liver microsomal and mito cytochrome P450s thru PXR and CAR nuclear receptors - the primary steroid and xenobiotic drug metabolism activators. But worse, far worse, it fucks with RXR and FXR, the retinoid and bile acid nuclear receptors. Kiss your immune system and liver biochemistry bye bye.
Not to mention what it does to renal tubules. But hey, liver and kidney regenerates. Doesn't it?
(nope, not under dnp - dinitrophenol - action)
For those not paying adequate attention here: dnp - dinitrophenol - is chauffered out of the body by binding to glutathione. Its sucks it out of liver and it activates drug detox mechanisms that are a sure bet for forming DNA adducts with the ROS activated form of DNP, once glutathione is depleted.
__________________