Dude, what you asking is the same as expecting an answer to the question "whats your favorite color". There is no right or wrong answer here.
Take the letro for a while and see how you react to it and if the lump goes away. Everyone responds differently and a large part of how someone responds depends on what shape your HPTS is currently in.
If you were half this damn persistent about getting info BEFORE you went and ran a cycle without an anti-e you wouldnt be in this spot now.