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Ok i felt it was about time i posted this up and we got more familiar with one of the most powerfull bodybuilding tools available.
IGF1-LR3 What is it?
IGF-1 is basically a polypeptide hormone that has the same some of the same molecular properties as insulin. IGF dose actually stand for insulin-like growth factor. IGF-1 is mainly responsible for long bone growth in children and it also affects muscle growth and repair of adults. Long R3 IGF-1 is a more potent version of IGF-1. It's chemically altered i like to think "enhanced" to prevent deactivation by IGF-1 binding proteins in the bloodstream. This results in a longer half-life of 20-30 hours instead of 20 min... So that means a far more effective version than the short chain we we re perhaps more familiar with.
IGF1-LR3 What does it do?
IGF-1LR3 greatly boosts muscle mass by inducing a state of muscle hyperplasia (increase in number of new muscle cells) in the MUSCLE WHERE ITS INJECTED!!
So think of it as muscle cell proliferation, or even the splitting of the cell so 1 becomes 2... Thats why its perfect on cycle when you get increased muscle cell growth too.
But why is IGF better than HGH? The reason being is HGH causes IGF levels to rise in the liver first, then then the muscle, Whereas IGF-LR3 causes localised IGF levels to rocket.
What other benefits?
Taken froma study in germany..
"Tissue build up is one of the main features of IGF-1, so I'd say it's of greater value. IGF-1 can genetically change muscular and cellular counts within the body; it can also enhance the body's ability to regenerate damaged tissue. In fact, IGF-1 is now under intensive research for its potential to repair tissue in burn patients, and for its regenerative effects on AIDS patients suffering from muscular wasting. Immediate effects are, of course, impossible to observe since it takes a respectable amount of time to see any visible changes in muscular repair"
But muscle size and shape can be seen quite quickly through a course of IGF-LR3
Doseage and use..
The best dose for muscle cell proliferation is 40mcg bi-lateraly for men, and 20mcg for women... so 40mcg in one bicep and 40mcg in the other Pre-workout.
And 20 in each bicep for women. This can be done in any 2 matching muscle groups.
This should be done for 40 days max and then have 30 days off.
What you need to be carefull of is adequate carb intake when using IGF, Especialy this version as its long lasting, it will literaly leech glucose to cause its localised muscle enhancing effects, similar to the way in wich insulin works, This goes on for 7-10 hours, You should take in 20g of carbs 5 grams slow release and 15 g fast, for every hour its active for the first 7 hours.. so it looks like this.
Based on a mans dose, so a women halfs this.
Pre-workout.. 40mcg bi-lateraly. Then pwo meal of 40g carbs, 30 slow release and 10g fast release carbs... that covers you for 2 hours.
Post-workout. 40 grams carbs 30 grams low gi or slow release, and 10g fast release carbs. That covers you for 2 more hours..
2 Hours later so 4 hours since the injection the same again... that takes you up to 6 hours, at this point just consume carbs when you feel the need... if you feel light headed, or any signs of hypoglycemia.
Some people prefer to dose 70 g carbs with there pre-workout meal, and 70 grams of carbs 4 hours later, but themost anabolic option is the one i outlined, causing a constant supply of everything you need to maximise its effects.
Only dose on workout days and a maximum of 3 times a week.
Use a 1" insulin syringe and only inject directly into muscle, and reconstitue with Acetic acid, once reconstituted keep refrigerated and use within 6 months.
Why dose pre-workout?
When do you get muscle cell proliferation? This is when the muscle actualy breaks down during intense exercise, this causes localised IGF-1 levels to sky rocket, Thats why Arachadionic acid works, because it increased localised IGF-1 levels, causing an increased inflammatry response to muscle degradation or breakdown, So by using IGF-LR3 pre workout you recieve the benefits of Hyperplasia straight away, without waiting for nearly 2 hours to use your IGF.. So you increase the window of growth time period, during its most significant period.. You have just provided your muscle everything it needs for muscle growth at EXACTLY the right time.. before its broken down. Plus by eating your Pre workout meal you fuel your workout and allow for your muscles to take advantage of the huge pumps IGF-LR3 can cause as your muscles are flooded with nutrients, blood and increased localised IGF-1 levels.
Russians experiences.
Using the protocol i outlined above, after weeks of experimenting and trying new ideas i found great success.
I focused on my triceps and biceps, In 4 weeks of the above protocol i added a depth to my tricep horseshoe and shape that i havent seen in many other bodybuilders, and i increased the severity of my bicep peak, 0.5" increase in arm size, now that may not seem much, but when you think on most anabolic cycles that last 5 weeks or more those kind of gains are not really that common, i saw that as a big result especialy as i ran it stand alone, With no additional anabolics.
The next time i run it, i will incorporate Need2slin to increase liver igf-1 levels and increased insulin response so increasing the effectiveness of the igf-lr3.
Possible sides.
Lethargy is a big one as carbs are used to increase muscle cell proliferation and not used as readily for fuel.
The big one to watch out for is burning from the acetic acid when its reconstituted, and the Hypoglycemia, Always have plenty of carbs on hand in case the sides hit you hard!!!
Unleashing its anabolic power
Igf1-lr3 As you all know is the long acting version of igf-1, Taking its active potential up towards 20 hours, But along with its ability to stimulate the growth of satalite muscle cells and helping them to mature into new muscle fibers it holds the ability to increase the uptake of many supplements we currently use, And it can cause the enhanced recovery of testicle size, and prevent muscle loss even in PCT.
Plus another reason its so potent is because of the decreased binding of Long R3 IGF-1 to all known IGF binding proteins. These binding proteins normally inhibit the biological actions of IGF.. not so with this long acting version.
Heres a quote from one of the top research doctors in the world, Dr sweeny the chairman of bioethics in 2002.
H. Lee Sweeney, Ph.D., Professor and Chairman of Physiology at the University of Pennsylvania and a recognized expert on the subject of the genetic enhancement of skeletal muscle, spoke to the World Anti-Doping Association with regard to the muscle building and regenerating properties of IGF-1.
"Rats that were given IGF-1 and did nothing were bigger and stronger than rats that weren’t given IGF-1 but exercised. And I’ll bet you guessed that rats that were given IGF-1 and exercised were the biggest, strongest rats in the house. The positive effects of IGF-1 on the rats continued for months after the rats stopped getting the supplemental hormone, whereas the exercising rats immediately lost size and strength as soon as they stopped exercising.
In another study the muscle fibers of 27-month old rats – old age for rats – that were given IGF-1 during middle age, exhibited no deterioration of muscle fibers that indicate the classic and inevitable signs of aging. These rats did not lose any fast twitch muscle fibers – the fibers responsible for power and speed – and had the same speed and power output that they had when they were six months of age.
To quote Dr. Sweeney, “So we were able to conclude that IGF-1 could prevent all of the hallmarks of age-related atrophy and loss of skeletal muscle function in mammalian aging, at least based on the rodent model, and now we’re hoping to pursue this in larger animal models.”
So how about IGF1-LR3, as those quotes were about plain igf?
According to Chemical Muscle Enhancement, a well-known underground PED guidebook written by Internet steroid guru L. Rea and available via download or through Amazon, IGF-1 has even been altered to increase its effectiveness, making IGF-1 ten times more potent (pages 134-136 of Chemical Muscle Enhancement). Several websites make reference to this altered form of IGF-1 – known as DES (1-3) IGF-1. This version of IGF-1, Insulin-like Growth Factor is also refereed to as Lr3IGF-1 (Note: Lr3IGF-1 is 2-3x more potent than regular IGF-1).
So increased potency, increased muscle retention... what else?
Well it increases the effectivness of an anabolic cycle, this is because of a very unique quality of igf-1-lr3, you see IGF-1 acts on several different tissues to enhance growth. IGF1 belongs in the ’superfamily’ of substances known as ‘growth factors,’ along with epidermal , transforming; platelet derived fibroblast, nerve, and ciliary neurotrophic growth factors. None of the other factors have any bearing on exoskeletal tissue incidentally however These agents all have in common the ability to stimulate cell division, known as mitogenesis, and cell differentiation. Meaning That In the case of IGF1 which does act on muscle tissue it will initiate the growth of new muscle fibers, and subsequently new receptors for testosterone. Many Users here on N2BM and on other forums have unanimously concluded that it enhances cycles of steroids significantly. They also seem to be adamant about its ability to reduce fat and improve vascularity a great deal.
Another suprising effect that remains largely unexplained is that it actualy Reverses testicular atrophy
Testicles if shrunken will return to “full swing” as it were even in the middle of a steroid cycle. If not shrunken they will not shrink during the cycle. This may explain partially why gains are kept after the cycle.
So imagine using this and HCGenerate on cycle, imagine the recovery in pct afterwards with full sized testicles!!
IGF-1 can be enhanced still further with an insulin mimicker, And Need2slin will cause even greater elevations in localised IGF-1 and the potential for more muscle growth and fat loss through its unique ability to drain fat cells and supply muscle cells with vital nutrients.
And theres more..
IGF-1 because of its action of forcing nutients into the muscle, it increases the uptake of amino acids!!! Yes think GEAR by N2BM and youve got the most potent amino acid supplement on the market as it uses the most biovailable protein growth factors, and every bit of it being force fed into the muscle by IGF-1, not only that but every supplement you take on cycle will have added benefits and biovailability, Better cycles, better PCT, And IGF-1 can be used as a bridge between cycles, added to Phytoserms, Dermacrine, Need2slin, and Gear you have an awesome bridge cycle but the options are endless, you now have the power to achieve you dreams, the choice is in your hands.
Russians anabolic peptide rating 9/10
Kind regards RS
Remember to support our peptide sponsor, Opresource.net.
IGF1-LR3 What is it?
IGF-1 is basically a polypeptide hormone that has the same some of the same molecular properties as insulin. IGF dose actually stand for insulin-like growth factor. IGF-1 is mainly responsible for long bone growth in children and it also affects muscle growth and repair of adults. Long R3 IGF-1 is a more potent version of IGF-1. It's chemically altered i like to think "enhanced" to prevent deactivation by IGF-1 binding proteins in the bloodstream. This results in a longer half-life of 20-30 hours instead of 20 min... So that means a far more effective version than the short chain we we re perhaps more familiar with.
IGF1-LR3 What does it do?
IGF-1LR3 greatly boosts muscle mass by inducing a state of muscle hyperplasia (increase in number of new muscle cells) in the MUSCLE WHERE ITS INJECTED!!
So think of it as muscle cell proliferation, or even the splitting of the cell so 1 becomes 2... Thats why its perfect on cycle when you get increased muscle cell growth too.
But why is IGF better than HGH? The reason being is HGH causes IGF levels to rise in the liver first, then then the muscle, Whereas IGF-LR3 causes localised IGF levels to rocket.
What other benefits?
Taken froma study in germany..
"Tissue build up is one of the main features of IGF-1, so I'd say it's of greater value. IGF-1 can genetically change muscular and cellular counts within the body; it can also enhance the body's ability to regenerate damaged tissue. In fact, IGF-1 is now under intensive research for its potential to repair tissue in burn patients, and for its regenerative effects on AIDS patients suffering from muscular wasting. Immediate effects are, of course, impossible to observe since it takes a respectable amount of time to see any visible changes in muscular repair"
But muscle size and shape can be seen quite quickly through a course of IGF-LR3
Doseage and use..
The best dose for muscle cell proliferation is 40mcg bi-lateraly for men, and 20mcg for women... so 40mcg in one bicep and 40mcg in the other Pre-workout.
And 20 in each bicep for women. This can be done in any 2 matching muscle groups.
This should be done for 40 days max and then have 30 days off.
What you need to be carefull of is adequate carb intake when using IGF, Especialy this version as its long lasting, it will literaly leech glucose to cause its localised muscle enhancing effects, similar to the way in wich insulin works, This goes on for 7-10 hours, You should take in 20g of carbs 5 grams slow release and 15 g fast, for every hour its active for the first 7 hours.. so it looks like this.
Based on a mans dose, so a women halfs this.
Pre-workout.. 40mcg bi-lateraly. Then pwo meal of 40g carbs, 30 slow release and 10g fast release carbs... that covers you for 2 hours.
Post-workout. 40 grams carbs 30 grams low gi or slow release, and 10g fast release carbs. That covers you for 2 more hours..
2 Hours later so 4 hours since the injection the same again... that takes you up to 6 hours, at this point just consume carbs when you feel the need... if you feel light headed, or any signs of hypoglycemia.
Some people prefer to dose 70 g carbs with there pre-workout meal, and 70 grams of carbs 4 hours later, but themost anabolic option is the one i outlined, causing a constant supply of everything you need to maximise its effects.
Only dose on workout days and a maximum of 3 times a week.
Use a 1" insulin syringe and only inject directly into muscle, and reconstitue with Acetic acid, once reconstituted keep refrigerated and use within 6 months.
Why dose pre-workout?
When do you get muscle cell proliferation? This is when the muscle actualy breaks down during intense exercise, this causes localised IGF-1 levels to sky rocket, Thats why Arachadionic acid works, because it increased localised IGF-1 levels, causing an increased inflammatry response to muscle degradation or breakdown, So by using IGF-LR3 pre workout you recieve the benefits of Hyperplasia straight away, without waiting for nearly 2 hours to use your IGF.. So you increase the window of growth time period, during its most significant period.. You have just provided your muscle everything it needs for muscle growth at EXACTLY the right time.. before its broken down. Plus by eating your Pre workout meal you fuel your workout and allow for your muscles to take advantage of the huge pumps IGF-LR3 can cause as your muscles are flooded with nutrients, blood and increased localised IGF-1 levels.
Russians experiences.
Using the protocol i outlined above, after weeks of experimenting and trying new ideas i found great success.
I focused on my triceps and biceps, In 4 weeks of the above protocol i added a depth to my tricep horseshoe and shape that i havent seen in many other bodybuilders, and i increased the severity of my bicep peak, 0.5" increase in arm size, now that may not seem much, but when you think on most anabolic cycles that last 5 weeks or more those kind of gains are not really that common, i saw that as a big result especialy as i ran it stand alone, With no additional anabolics.
The next time i run it, i will incorporate Need2slin to increase liver igf-1 levels and increased insulin response so increasing the effectiveness of the igf-lr3.
Possible sides.
Lethargy is a big one as carbs are used to increase muscle cell proliferation and not used as readily for fuel.
The big one to watch out for is burning from the acetic acid when its reconstituted, and the Hypoglycemia, Always have plenty of carbs on hand in case the sides hit you hard!!!
Unleashing its anabolic power
Igf1-lr3 As you all know is the long acting version of igf-1, Taking its active potential up towards 20 hours, But along with its ability to stimulate the growth of satalite muscle cells and helping them to mature into new muscle fibers it holds the ability to increase the uptake of many supplements we currently use, And it can cause the enhanced recovery of testicle size, and prevent muscle loss even in PCT.
Plus another reason its so potent is because of the decreased binding of Long R3 IGF-1 to all known IGF binding proteins. These binding proteins normally inhibit the biological actions of IGF.. not so with this long acting version.
Heres a quote from one of the top research doctors in the world, Dr sweeny the chairman of bioethics in 2002.
H. Lee Sweeney, Ph.D., Professor and Chairman of Physiology at the University of Pennsylvania and a recognized expert on the subject of the genetic enhancement of skeletal muscle, spoke to the World Anti-Doping Association with regard to the muscle building and regenerating properties of IGF-1.
"Rats that were given IGF-1 and did nothing were bigger and stronger than rats that weren’t given IGF-1 but exercised. And I’ll bet you guessed that rats that were given IGF-1 and exercised were the biggest, strongest rats in the house. The positive effects of IGF-1 on the rats continued for months after the rats stopped getting the supplemental hormone, whereas the exercising rats immediately lost size and strength as soon as they stopped exercising.
In another study the muscle fibers of 27-month old rats – old age for rats – that were given IGF-1 during middle age, exhibited no deterioration of muscle fibers that indicate the classic and inevitable signs of aging. These rats did not lose any fast twitch muscle fibers – the fibers responsible for power and speed – and had the same speed and power output that they had when they were six months of age.
To quote Dr. Sweeney, “So we were able to conclude that IGF-1 could prevent all of the hallmarks of age-related atrophy and loss of skeletal muscle function in mammalian aging, at least based on the rodent model, and now we’re hoping to pursue this in larger animal models.”
So how about IGF1-LR3, as those quotes were about plain igf?
According to Chemical Muscle Enhancement, a well-known underground PED guidebook written by Internet steroid guru L. Rea and available via download or through Amazon, IGF-1 has even been altered to increase its effectiveness, making IGF-1 ten times more potent (pages 134-136 of Chemical Muscle Enhancement). Several websites make reference to this altered form of IGF-1 – known as DES (1-3) IGF-1. This version of IGF-1, Insulin-like Growth Factor is also refereed to as Lr3IGF-1 (Note: Lr3IGF-1 is 2-3x more potent than regular IGF-1).
So increased potency, increased muscle retention... what else?
Well it increases the effectivness of an anabolic cycle, this is because of a very unique quality of igf-1-lr3, you see IGF-1 acts on several different tissues to enhance growth. IGF1 belongs in the ’superfamily’ of substances known as ‘growth factors,’ along with epidermal , transforming; platelet derived fibroblast, nerve, and ciliary neurotrophic growth factors. None of the other factors have any bearing on exoskeletal tissue incidentally however These agents all have in common the ability to stimulate cell division, known as mitogenesis, and cell differentiation. Meaning That In the case of IGF1 which does act on muscle tissue it will initiate the growth of new muscle fibers, and subsequently new receptors for testosterone. Many Users here on N2BM and on other forums have unanimously concluded that it enhances cycles of steroids significantly. They also seem to be adamant about its ability to reduce fat and improve vascularity a great deal.
Another suprising effect that remains largely unexplained is that it actualy Reverses testicular atrophy
Testicles if shrunken will return to “full swing” as it were even in the middle of a steroid cycle. If not shrunken they will not shrink during the cycle. This may explain partially why gains are kept after the cycle.
So imagine using this and HCGenerate on cycle, imagine the recovery in pct afterwards with full sized testicles!!
IGF-1 can be enhanced still further with an insulin mimicker, And Need2slin will cause even greater elevations in localised IGF-1 and the potential for more muscle growth and fat loss through its unique ability to drain fat cells and supply muscle cells with vital nutrients.
And theres more..
IGF-1 because of its action of forcing nutients into the muscle, it increases the uptake of amino acids!!! Yes think GEAR by N2BM and youve got the most potent amino acid supplement on the market as it uses the most biovailable protein growth factors, and every bit of it being force fed into the muscle by IGF-1, not only that but every supplement you take on cycle will have added benefits and biovailability, Better cycles, better PCT, And IGF-1 can be used as a bridge between cycles, added to Phytoserms, Dermacrine, Need2slin, and Gear you have an awesome bridge cycle but the options are endless, you now have the power to achieve you dreams, the choice is in your hands.
Russians anabolic peptide rating 9/10
Kind regards RS
Remember to support our peptide sponsor, Opresource.net.
