Steve Harris about periferal serotonin:
5-hydroxytrytophan (5-HTP) is what's sold as a serotonin brain
precursor. It is taken up into the brain. If you could keep if from
getting converted to serotonin in the liver, you'd be in great shape.
Taking 10 mg of B6 a day, however, is going to get most of it converted
to serotonin before it has a chance to get into the brain. 50 mg a day
without carbodopa is too much, since most of it will get converted to
serotonin, and 50 mg a day of "outside the brain" serotonin or so is
about the amount associated wtih heart damage in carcinoid syndrome.
Steve Harris, M.D.