The quads, delts and biceps are the best places for me. I have to give myself my shots there because I cant reach my ass!!! LOL anyway bro when it come to quad shots the pain will go away for the most. It is like they get used to it for the most part. You will fine sweet spots on your quads " or any other body part" but you just have to do trial and errior. But when you do find thoses sweet spots whit no pain be sure and rotate so not to build up scar tissue. Best of luck