Beware the effects of Anastrazole

[Zyglamail]

Anything that lowers estrogen values can be detrimental to cholesterol, thas has been stated many times in the past. Cycling in general, if you do not have ALL values within norm should be avoided because no matter what you use, AAS, anti-e etc they will all wreak havoc on your system. Just another reason I feel 8-10 week cycles are more than enough with ample recovery time in between.

NFG123, avoid saturated fats and concentrate on good omega fats, hope the levels come down for you and all is good, keep us posted.

 

[ryker77]

My total cholestrol and trig were all jacked up from l dex. From now on I'll no longer take l-dex at more than 1mg ED. I think the most effective and safest method would be a small dose of ldex EOD and nolvadex 20mgs ED.

and of course omega and flax seed oils.

 

[Ulter]

I must be way behind on this. All the literature I read says it's the AAS and not the Arimidex causing cholestrol levels to rise. Since you're E levels are not lowered beyond basal with Arimidex while you're cycling, at least not mine, I don't see how it could be the Arimidex.

 

[Zyglamail]

That is a good point Ulter, most people when cycleing and using ana or let will still have E levels 2-3x higher than normal. Anti-e's (3rd generation anyways) typically do have a negative effect on lipid profiles in tests, but the test subjects are usually not using AAS.

 

[Triple J]

Let's be clear here - the nolva and clomid look like e to the liver, thus encouraging it to behave as if e was in the body, and wroking to improve lipid profiles. The ldex and other anti-a's will eliminate e from being formed and result in worse lipid profile if that is an issue for you. For this reason, taking nolva throughout the cycle should be helpful, even if taking ldex. Lower doses could probably help matters as well.

 

[40butpumpin]

People are dying from CV disease every day with so-called normal cholesterol. Lipid profiles are indicators, nothing else. In older people with other high risk factors this is a red flag. In young, in shape people, with a reason for it being ascew (AAS, Arimidex), it's a VERY different story. THIS IS NOT A DEATH SENTENCE. Think about it, what the hell is high cholesterol? It certainly is not heart disease or mean that you're going to die of a heart attack! Your concern should be homocysteine and arterial inflamation defined my a marker called C-reactive protein. Now if these two are off then you are headed for trouble. B6, TMG, B12, EFA'a (Perilla and Flax Oil), very low dose aspirin, GLA/DHA fish oils are all EXCELLENT for CV health. I'm not trying to act like a doctor here, flame the hell out of me if I am. However, I'm tired of people scared shitless as a result of pharmacuetical industy scare tactics. If you really want to get to some meat here, what really causes heart disease is calcification of the arteries. This is for the most part caused by chronic homocycteine levels and a bacteria called nanobacteria. So if you really want to protect yourself get some chelation therapy; there's now protocols that have BEEN PROVEN by CAT scans to all but completely clear up calcified (hardened) arteries. Come on guys, let's get over this fear of a poor lipid profile lab report, especially if you're young, in shape and are living a clean lifestyle. If you believe me then give me some damn karma, if not, do some research yourself.

 

[BigAndy69]

Good post 40

 

[Komo]

Triple J!

How do you think the liver recognizes the nolva and clomid? Through the estrogen receptor? I don´t think so!!! They both antagonize the estrogen receptor....

There is no magic way of the liver to recognize estrogen besides attaching to and triggering the "ere" (estrogen response element) on the DNA. They attach, dut don´t trigger the receptor, which is the whole point of using them...

No I´m with ulter and zyglamail on this one..

/Komo

 

[gnp]

Ask your doc about lipitor if you have High cholesterole... It Helps.

 

[Triple J]

Triple J!

How do you think the liver recognizes the nolva and clomid? Through the estrogen receptor? I don´t think so!!! They both antagonize the estrogen receptor....

There is no magic way of the liver to recognize estrogen besides attaching to and triggering the "ere" (estrogen response element) on the DNA. They attach, dut don´t trigger the receptor, which is the whole point of using them...

No I´m with ulter and zyglamail on this one..

/Komo

I think there is some confusion here. Nolva and clomid mimick estrogen and bind to estrogen receptors, their affinity for e-receptors throughout the body varies. The important point in regards to lipids, is to the liver, they look to be an estrogen, thus encouraging the liver, to process cholesteral in a manner which improves lipid profiles as compared to, if no or very little estrogen was present.

Regardless of what caused the condition of very low estrogen (AAS or 3rd generation anti-a's), nolvadex will substitute for e in a manner which should improve a poor lipid profile. Additionally, it would provide a measure of protection against developing the condition.

I have experiences this first hand while taking arimidex and clomid, and I believe there is research to back it up, if someone wants to go digging for it.

What may be important to keep in mind is that while estrogen warrants some control, it should not be eliminated. If it is driven to very low levels for any length of time, nolvadex can help protect against development of harmful lipid profiles.

Now if poor lipid profiles are not a concern to you, fine. In my case I felt much better after my lipid profiles returned to normal.