here ya go, that was easy
its just a press release though
THE FOLLOWING NEWS RELEASE WAS ISSUED BY THE CANADIAN INSTITUTES OF HEALTH
RESEARCH.
NEW CANADIAN MENSTRUAL CYCLE RESEARCH MAY ALTER MEDICAL TEXTS
OTTAWA (July 7, 2003) - A Canadian research team funded by the Canadian
Institutes of Health Research (CIHR) has uncovered evidence that suggests
the traditionally accepted model of the human menstrual cycle is wrong.
The discovery by University of Saskatchewan researchers may lead to the
design of new, safer and more effective contraception and may improve
success with assisted reproductive technology for women who are having
trouble conceiving.
"This collaborative discovery is an important step forward in understanding
the human menstrual cycle," said Dr. Michael Kramer, Scientific Director of
the Institute of Human Development and Child and Youth Health of the
Canadian Institutes of Health Research. "It provides a new model for ovarian
function during the menstrual cycle which could have profound implications
for infertility diagnoses and treatment in women."
The team's findings were published in the July 6th issue of the prestigious
scientific journal Fertility and Sterility. A companion paper published in
Biology of Reproduction is available on-line.
Previous research has shown that a group of 15 to 20 follicles grew during
the menstrual cycle, and that one follicle from the group was selected to
ovulate while the others died off.
University of Saskatchewan researchers have found that this process occurs
in "waves". In response to hormone surges, women experience two to three
periods of follicular development each month, though only one egg is
selected for ovulation.
"This work is particularly exciting to us because of the impact it will have
on women taking oral contraceptives and undergoing fertility treatment,"
says Dr. Roger Pierson, Director of the Reproductive Biology Research Unit
at the U of S. "It also shows that we have not fully understood the basic
biological processes that occur during menstrual cycles. We are literally
going to have to re-write medical textbooks."
For instance, up to 40 per cent of women may not be able to use natural
family planning methods, he said. That's because for women who experience
two or three waves of dominant follicle growth per month there is no "safe"
time to have intercourse during the cycle -- there may always be a follicle
capable of ovulating.
The study involved 63 women with normal menstrual cycles who underwent
ultrasound every day for a month. "This study is a real tribute to the
altruism of Saskatchewan women," Dr. Pierson said. "As I've gone around the
country talking about this work, people just can't believe the dedication of
our research volunteers."
Dr. Pierson says further research is needed to see if the same number of
waves occurs consistently every month and to determine why a particular egg
is selected to ovulate.
Other team members are Angela Baerwald, the lead author on the article who
just received her Ph.D. in clinical reproductive biology from the U of S,
and veterinarian Dr. Gregg Adams, a professor with the Western College of
Veterinary Medicine at the University of Saskatchewan.
The study was done through an unusual collaboration. In clinical studies,
Dr. Pierson noticed follicular development occurring at a time when the
textbooks said it shouldn't happen. He consulted Dr. Adams, who developed
the follicular wave model in cows with Dr. Pierson at the University of
Wisconsin in the 1980s.
"What Roger was seeing in women seemed very similar to what is happening in
horses and cows that develop follicles in waves," said Dr. Adams. "And
that's exactly what we found -- that humans are not so very different from
other species."
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For further information, contact:
Dr. Roger Pierson
College of Medicine
Department of Obstetrics, Gynaecology and Reproductive Sciences
University of Saskatchewan
(306)-966-4458
Janet Weichel McKenzie
CIHR Communications
(613) 941-4563
[email protected]
Kathryn Warden
University of Saskatchewan Research Communications
(306) 966-2506
[email protected]
www.usask.ca/research