not really, its great medicine. like i said keeps me up if i do not take it at about 5:30am then go back to bed(because it takes about 2 hours to fully kick in) or else i cant get to bed. when taken on a completely empty stomach, may make me a little jittery. I love the stuff, it does not feel like any kind of stimulant, just alert and awake. as i said, it is new(so have to see if insurance will cover it), and not highly controlled, so it is relatively easy to get a script from a doc.
hope this helps
remember, it is called Provigil(modafinil)