I get compliments on my eyes a lot. My head is shaved and I have really bright green eyes so that is usually the first thing that people notice.
I just say thanks, ask her what her name is and then introduce myself using my 1st and last name. Nobody ever does that and it shows a ton of self confidence.
Then just be yourself. If you try to force out a witty line, it's probably gonna come off as cheesey. just my 0.02