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Study showing winstrols activity independent of A/R binding/DNA interaction...
- Thread starter HUCKLEBERRY FINNaplex
- Start date
The Man Child
New member
So what you're saying is that it is much more beneficial to do a Test/EQ/Winny cycle as opposed to a Test/EQ/Deca cycle? Because the second cycle only hits Class 1 receptors, and the first cycle hits both types. Do I have this right?
So basically it means you should stack a Test (whatever ester), a 17aa steroid, and maybe if you want some other type of Class 1 steroid. For optimal results. This is basically common sense, but good that there is scientific results to back it.
So basically it means you should stack a Test (whatever ester), a 17aa steroid, and maybe if you want some other type of Class 1 steroid. For optimal results. This is basically common sense, but good that there is scientific results to back it.
Andy-No,I don't believe that it's nearly that high of an amount.Look at testosterone,widely considered by most bodybuilders to be the grand-daddy of all muscle builders.Nothing puts mass on as efficiently as it,except for maybe tren.But unlike tren,testosterone only has 'mediocre' binding capacity to the A/R,being far outshined by deca and primo in the binding capacity department.Yet it provides much better overall growth.Why?It outshines the above aforementioned anabolics in the Class-II mechanisms,such as influences on GH,IGF-1,activation of satellite cells into full maturation,activation of prostaglandin receptors,etc...I believe that non-A/R mediated activity is UNDERRATED if anything on it's influences on growth.
Man child-That's exactly right.There are two steroids that possess DUAL activity(both class-I & II),and that is testosterone and tren.For this reason,they should form the base of your cycle.Tren has the strongest binding capacity to the androgen receptor of ANY steroid,therefore adding a class-I with it probably isnt necessary,as it's more than sufficient in that department.It's class-II activity isn't as aggressive ,therefore adding in a class-II oral such as winstrol or dianabol would work very well.As for testosterone,,the same applies.Throw in an oral compound and a class-I,such as deca,eq,or primobolan,and you've got all the bases for anabolism completely covered.Now all you need is the right training stimuli,and ample nutrition,and you're on your way to explosive growth...
Man child-That's exactly right.There are two steroids that possess DUAL activity(both class-I & II),and that is testosterone and tren.For this reason,they should form the base of your cycle.Tren has the strongest binding capacity to the androgen receptor of ANY steroid,therefore adding a class-I with it probably isnt necessary,as it's more than sufficient in that department.It's class-II activity isn't as aggressive ,therefore adding in a class-II oral such as winstrol or dianabol would work very well.As for testosterone,,the same applies.Throw in an oral compound and a class-I,such as deca,eq,or primobolan,and you've got all the bases for anabolism completely covered.Now all you need is the right training stimuli,and ample nutrition,and you're on your way to explosive growth...
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huck, as always great info brother!!!!!!
yet what is to be said of oxandrolone in this regard? ox binds well to the AR and is more a class-I than a class-II AS. ive heard that stano and ox are a synergistic combo provided you love your liver......lol.
so huck......with ox being an exception to the class-II rule of most 17-AA AS, what would you reccomend if one were looking to stack oxandrolone?
Unity66
yet what is to be said of oxandrolone in this regard? ox binds well to the AR and is more a class-I than a class-II AS. ive heard that stano and ox are a synergistic combo provided you love your liver......lol.
so huck......with ox being an exception to the class-II rule of most 17-AA AS, what would you reccomend if one were looking to stack oxandrolone?
Unity66
Well unity,and I'm starting to get excited over this,I'm starting to come across evidence that ox may very well be a DUAL mechanismed anabolic as well!I'll keep digging through abstracts over the next few months and see what concrete evidence I can come up with.One thing's for sure though,ox is definitely potent at the A/R.Testosterone would make a great partner to ox,and like you said stanozolol(with a healthy dose of alpha-lipoic acid/milk-thistle)would compliment it nicely as well...
say no more.......ive picked-up a healthy dose of this wonderful substance that, untill recently, has been out of my price range. with the generics fonz recently tested from DSPO's and my batches................im planning to bridge for the first time with oxandrolone through all of next semester........after i restore homeostasis and get an edoscreen done....
once i finish this test/tren/dbol/liquidex/t-3/clen bout...........im leaning up nicely and damn am i feeling full in the proccess
keep digging juice willis...heh!!!
Unity66
once i finish this test/tren/dbol/liquidex/t-3/clen bout...........im leaning up nicely and damn am i feeling full in the proccess
keep digging juice willis...heh!!!
Unity66
Andy13 said:
Muscle Growth is probably 90%+ AR mediated, it is not dependant on a whole lot of factors, Nitrogen retention=size gain.
Strength gains are derived from CNS adaptation, which is where Halo, Winny, and Methyl-DHT work. Not that AR and hypertrophy don't play role in strength increase. Other class 2 effects include phos-creatine synthesis being amplified such as with anavar(which also binds to the AR).
Important to note that while the substance may have a high affinity for the AR, that doesn't mean that it's particularly antagonistic. Some molecules will bind more or less strongly to the AR and may elicit far different effects based on their structure.
So the effects of a stong androgen (trenbolone) will be aided by simultaneous use of a class 2 like methyl-dht plus anavar for increased ATP.
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