While the conclusion of the article is disturbing, I have to again repeat my original quote "This is very interesting if in fact it is credible". This is the only study I can so far find that has come to this conclusion. There is room for doubt here. Additionally if in fact this is a good conclusion, the loss of gains was not quantified. In other words there would be no good way to tell what could have happened if a given bodybuilder had not taken Milk Thistle in a cycle. The fact is, as we all know it is very rare we see real studies that use subjects such as our selfs who run an amazing array and combination of performance enhancing drugs. At least on the surface I would believe from my experience and others around me that if in fact milk thistle affected our gains it was minor. I posted the article, just in the case it had some merit and as food for thought. Most of us here want all we can get out of our cycles and if there is a chance this is hindering us, then at least for me I will consider other options for a few cycles and watch the results.