Few, to none, know f'all about how receptors work. It just sounds like they do.I’m not sure how they would compete for receptors as GW activates PPAR and SR activates circadian nuclear receptors REV-ERBα and -β. Although they both increase the density of mitochondria in the cell, I would assume this would create a synergistic effect. Correct me if I’m wrong any vets out there, but every time I’ve stacked these together, I’ve seen incredible results.