GH and Insulin experts,need your help

[rj420]

yep

Steveo is right on with that. Increase in insulin means decrease in GH levels.

 

[TPH]

I would take the slin at the same time as the GH as they will peak at the same time, which will help with the possible fat deposits brought on by slin.

Most of the Vets on the Board rec. taking teh Gh and 'slin togther post workout.

 

[TPH]

Ahhh Yes, GH and Slin - TOGETHER

From Anabolics.com


Growth hormone (GH) is one of the most sought after bodybuilding drugs due to its' legendary abilities to strip off body fat and increase muscle mass. The former is accomplished through direct lipolysis (fat release from adipocytes), which GH does to an incredible degree. Muscle mass acquisition is accomplished through: the direct stimulation of protein synthesis, increasing amino acid uptake by muscle cells, and by greatly stimulating IGF-1 synthesis in the liver. It is this last point that is of interest to us because it is the main anabolic mechanism for GH, and it is also where insulin comes in to play. More than half of GHs' anabolic effect is due to IGF-1 production, but unfortunately this is quite often wasted. This is because IGF-1 has an extremely short half life in the bloodstream, so it usually doesn't reach many target tissues (muscles for our interest) to exert maximum anabolic effect. To rectify this situation, insulin can be used to increase the amount of an IGF-1 binding protein (specifically IGF1-BP3) that actually helps IGF-1 to reach the muscles and exert its' extreme anabolism. Insulin also reduces the amount of "bad" IGF1 BP's, (BP's 2 and 4) that would normally interfere with IGF-1 uptake and use by muscle. To say that there is a synergistic effect between insulin and GH doesn't do the combination justice. It makes me shudder to think of the hundreds of thousands of dollars spent on GH, without using it to the maximum anabolic potential. From a fat loss perspective, GH is incredible. It should directly negate the lipogenic effect of insulin, leaving you with one KICK ASS combination.

 

[steveo]

I disagree with TPH. GH should not be taken right after your workout because your natural GH levels are already peaking from your workout, also it should not be taken right before bed because you dont want to interfere with your natural GH release. You are suppose to space out your Gh and insulin shot. You should take the GH and then wait 2 hours before taking your insulin shot. Taken them together at once will negate the GH. If that statement that TPH put is from Jeff Summers well then all i have to say is Anything that comes out of Jeff Summers mouth is total garbage. I would listen to my mother before i listened to him on GH or Steroid use

 

[TPH]

steveo: I agree that it is not optimal to take the GH or insulin for that matter before bed. For me, I train late at night, so that is when I believe it is most optimal to take the insulin since that is when I take the glut. and creatine.

I am not a chemist or a doctor, but I have studied up on this a bit. Regarding the statement that GH and insulin work well together do you disagree that insulin can be used to increase the amount of IGF1-BP3? Which in turn helps IGF-1 to reach the muscles.

At any rate, we should keep this bumped because I believe most of the Vets and Mods have suggested taking the GH and insulin together.

Thanks

 

[steveo]

TPH, I agree with you that insulin can be used to increase the amount of IGF-BP3, which does help IGF-1 reach the muscles. It’s speculated that GH stimulates uptake of about half of the 9 or so essential amino acids into muscle, while insulin stimulates the uptake (or prevents the loss) of the complimentary half. However I was always taught that they should be spaced out at about 2 hours from each other for maximum anabolic effect

 

[TPH]

steveo - Good Karma to you for the great info.

I am very soon starting a humilin R (5 units post wo) Gh (2 units in the am 2 units post wo), as a Bridge. Your points are well taken. I'll research this a bit more.

I hope we can keep this bumped for more opins.!!

Thanks

TPH

 

[greg21]

bump for more opinions.....Ironmaster, where are you?
I have always been taught to take the two together...but i would love to know anything that might work better.

 

[hockey1]

This is some great info,i take 10iu slin right after my a.m. workout,then half hour later take 3iu GH,I was told this is a good way to do it.So many different opinions

 

[ASTRAL FITNESS]

Bump this is a good topic.
elevated GH temporarily reduces insulin sensitivity I know this
I would think taking short acting insulin immeadiately after workout with high carb shake and then taking GH 1/2 to 2 hours later would conceivably work well. I'll have to research this a bit more