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Does Green tea extract without caffeine affect the adrenal system?
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Int J Obes Relat Metab Disord. 2000 Feb;24(2):252-8. Related Articles, Links
Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity.
Dulloo AG, Seydoux J, Girardier L, Chantre P, Vandermander J.
Institute of Physiology, University of Fribourg, Fribourg, Switzerland. [email protected]
The thermogenic effect of tea is generally attributed to its caffeine content. We report here that a green tea extract stimulates brown adipose tissue thermogenesis to an extent which is much greater than can be attributed to its caffeine content per se, and that its thermogenic properties could reside primarily in an interaction between its high content in catechin-polyphenols and caffeine with sympathetically released noradrenaline (NA). Since catechin-polyphenols are known to be capable of inhibiting catechol-O-methyl-transferase (the enzyme that degrades NA), and caffeine to inhibit trancellular phosphodiesterases (enzymes that break down NA-induced cAMP), it is proposed that the green tea extract, via its catechin-polyphenols and caffeine, is effective in stimulating thermogenesis by relieving inhibition at different control points along the NA-cAMP axis. Such a synergistic interaction between catechin-polyphenols and caffeine to augment and prolong sympathetic stimulation of thermogenesis could be of value in assisting the management of obesity. International Journal of Obesity (2000) 24, 252-258
Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity.
Dulloo AG, Seydoux J, Girardier L, Chantre P, Vandermander J.
Institute of Physiology, University of Fribourg, Fribourg, Switzerland. [email protected]
The thermogenic effect of tea is generally attributed to its caffeine content. We report here that a green tea extract stimulates brown adipose tissue thermogenesis to an extent which is much greater than can be attributed to its caffeine content per se, and that its thermogenic properties could reside primarily in an interaction between its high content in catechin-polyphenols and caffeine with sympathetically released noradrenaline (NA). Since catechin-polyphenols are known to be capable of inhibiting catechol-O-methyl-transferase (the enzyme that degrades NA), and caffeine to inhibit trancellular phosphodiesterases (enzymes that break down NA-induced cAMP), it is proposed that the green tea extract, via its catechin-polyphenols and caffeine, is effective in stimulating thermogenesis by relieving inhibition at different control points along the NA-cAMP axis. Such a synergistic interaction between catechin-polyphenols and caffeine to augment and prolong sympathetic stimulation of thermogenesis could be of value in assisting the management of obesity. International Journal of Obesity (2000) 24, 252-258
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should point out here that green tea is just unfermented black tea (the kind us brits favour).. green tea may contain more of the substances listed above.. but black tea still contains them....
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