Tren does not stress the liver, it's not 17aa. However, running tren E only weeks 5-10 is bad, it's a long ester and needs more time to kick in. I'd run the tren weeks 1-10, the test 1-10. Dbol 1-4, winny 8-12, start PCT right after winny is done. Keep the dbol at 30mg/day the whole time. And yes, lose some fat before you start the cycle. It is possible to bulk up then cut while on cycle, but you'll likely gain more fat than you need if you're already a bit heavy when you start.