I like denver's chances at home against the Colts. A key to this game is to establish a strong running attack against the Colts, who by the way have the worst run defense in the league. Running eats up the clock and keeps Manning where he belongs, on the sidelines.
Sucks that Lepsis is out though.
Denver is 2-2 against the Colts in the regular season and is at home with a damn good Defense.