The following was taken from an alternative medicine site:
"Ephedra and caffeine are very stressful on the adrenal glands because
they continually cause the secretion of epinephrine (adrenalin). This is
what causes one to feel "wired" and will definitely cause weight loss.
Even though you will experience weight loss, the adrenals take a major
beating and end up producing less and less of these important hormones
leading to poor health and a decrease in metabolism over time"
after reading through this and a bunch of other articles, the explanation for the moodiness (ie. anger, agressiveness, depression) related to the use of supplements containing ephedra is the over stimulation of the adrenal glands. These glands are responsible for our flight or fight responses. thus their over stimulation may result in the extreme moods.
also taken from a site:
"Nutritional supplements to support the adrenals include vitamin A, C, E,
B-5, B-complex, manganese, zinc, and adrenal glandulars (I recommend
Raw Adrenal by Enzymatic Therapy- it is a complete formula that I use
with my patients). Ginseng also supports the adrenals and can be
taken in pill, tea or extract form. "
i was curious myself since i am one who uses ephedra/ephedrine products. just thought i'd post this for others who are curious.