I should say that EXCESS heat/cooking is deleterious to amino acid availability. Particularly lysine, cysteine, histidine, tyrosine, and methionine that can form undisgestible cross-linked reactants, and creatine and carnitine which are also highly lost even at lower cooking temps. Moderate cooking of many proteins will actually improve the digestiblity if it's a long-chain tertiary or quaternarny protein. Whey protein hydrolyzate is not in this category, but eggs, beef and chicken are.
Of course EXCESS cooking of some proteins also creates carginogenic cyclic amines (ie the old burned barbecued meats).