I don't know what the Axe guys or a doctor will say but I have been on NOXCG3 during my cycle of PP. I'm mid cycle with the PP and will finish with SD and then ofcourse PCT. I had been taking the NOXCG3 probably a month prior to starting the cycle and have continued through. I have found, in my expierence, that it has helped to enhance my cycle. I can't find a logical reason how or why it would conflict other than liver or hydration issues. Stay hydrated, and take your liver protectant and I think you will be fine. Ofcourse this is just my humble opinion and you need to consult a doctor first and/or get some advice from the Axe guys. Good luck with your cycle bro and if you find out some conflicting information let me know.