The Future of Nutrient Delivery - Liqua-Vade

[Primordial Performance]

Dear Elite,

Primordial Performance is proud to present their new Liqua-Vade™ nutrient delivery technology. Liqua-Vade is literally a liquid nutrient invasion.

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Liqua-Vade technology is based off a pharmaceutical drug delivery technology known as a Self Emulsifying Drug Delivery System (SEDDS). (1-15) This technology was designed to enhance absorption of poorly water soluble compounds. This includes various hormones, flavonoids, and fat soluble vitamins (carotenoids, vitamin E, CoEnzyme Q-10, ect)

The technology enhances delivery of poorly soluble compounds by dissolving and making them highly dispersed in the digestive track. To see exactly how Liqua-Vade solubilizes poorly water soluble compounds, visit this page – Liqua-Vade

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Here are a few clinical trials of Liqua-Vade technology (SEDDS) enhancing delivery of poorly water soluble nutrients –

Poorly water soluble vitamin (CoQ10) -

Steroid hormone -

Isoflavone from kudzu root -

Flavone from silymarin (milk thistle extract) -

I’d like to thank you for reading this special announcement from Primordial Performance.

Yours in health & fitness,

Eric Potratz
Primordial Founder & President

Questions?

Phone – 1-800-568-2924
Email - [email protected]
Visit - Primordial Performance


References –

1. Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.
Porter C, et al
Nat Rev Drug Discov 2007 Mar;6(3):231-48

2. Lipid drug delivery and rational formulation design for lipophilic drugs with low oral bioavailability, applied to cyclosporine.
Odeberg et al.
Eur J Pharm Sci. 2003 Dec;20(4-5):375-82

3. Lipid microemulsions for improving drug dissolution and oral absorption: Physical and biopharmaceutical aspects
Constantinides PP et al.
Pharm Res. 1995 Nov;12(11):1561-72

4. Self-microemulsifying drug delivery systems (SMEDDS) for improving in vitro dissolution and oral absorption of Pueraria Lobata isoflavone.
Cui et al.
Drug Dev Ind Pharm. 2005 May;31(4-5):349-56.

5. Development of supersaturatable self-emulsifying drug delivery system formulations for improving the oral absorption of poorly soluble drugs.
Gao P, et al.
Expert Opin Drug Deliv. 2006 Jan;3(1):97-110

6. Enhanced oral bioavailability of Coenzyme Q10 by self-emulsifying drug delivery systems.
Balakrishnan P, et al.
Int J Pharm. 2009 Jun 5;374(1-2):66-72.

7. Clinical studies with oral lipid based formulations of poorly soluble compounds.
Fatouros DG, et al
Ther Clin Risk Manag. 2007 Aug;3(4):591-604

8. Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs.
R. Nesliham et al.
Biomed Pharmacother. 2004 Apr;58(3):173-82. Review.

9. Formulation of lipid-based delivery systems for oral administration: Materials, methods, and strategies
Pouton CW et al.
Adv Drug Deliv Rev. 2008 Mar 17;60(6):625-37. Epub 2007 Nov 4

10. Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound.
Susan et al.
Pharm Res. 1992 Jan;9(1):87-93.

11. Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water soluble drug
Greg A et al.
J Pharm Sci. 2005 Mar;94(3):481-92.

12. Cyclosporin nanoparticulate lipospheres for oral absorption
Tania et al.
J Pharm Sci. 2004 May;93(5):1264-70

13. Self-Emulsifying Drug Delivery Systems: Strategy for improving oral delivery of poorly water soluble drugs.
Jing et al.
Current Drug Therapy, 2007, 2, 85-93

14. Studies on preparation and absolute bioavailability of a self-emulsifying system containing puerarin.
Quan DQ, et al.
Chem Pharm Bull (Tokyo). 2007 May;55(5):800-3

15. Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system.
Wu W, et al
2006 Jul;63(3):288-94. Epub 2006 Mar 9

 

[Primordial Performance]

Here is an interview I just did with Carl on Liqua-Vade.

-Eric

 

[SouthernLord]

Awesome job Eric. I've seen some mention of this on other sites. I'm glad you're finally releasing it.

 

[Maxgolf]

Awesome job Eric. I've seen some mention of this on other sites. I'm glad you're finally releasing it.

Your tellin me! So when are we gonna see a SouthernLord Log

 

[dabuffguy]

This will enhance the uptake of all sorts of nutrients from A-Z right?

Sounds like another thing to add to my Post-workout to give it an extra boost.

 

[needtogetaas]

BTW guys the taste is pretty damn good to.. You know how when you was a kid you got the bubble gum flavored meds from the doc. Sneak in the fridge when Moms not looking to take a swig lol... Ya its kind og like that. So no worries about it tasting like crap.

Pm me for more info on this product. I am pretty happy they came out with a oral. Lots of people love the reg topical sustain but there is many who deff want something they don't have to rub on. Another winner for PP guys.

 

[needtogetaas]

PP is the master product chemist!!!!!!!!!!!!!!!!!

 

[DJ_UFO]

This will enhance the uptake of all sorts of nutrients from A-Z right?

Sounds like another thing to add to my Post-workout to give it an extra boost.

Well, that's the question I asked PP on the other thread. What you say makes sense depending on what he answers.

- Is it more effective using it on an empty stomach?
- Can be mixed with liquids and/or food?
- If it can be mixed, can the oral technology help the absorption of nutrients that it is being mixed with? like protein or vitamins?

I have the gut feeling that the product is designed at the right ratio formula and should work better on an empty somach by itself. But probably pp will answer tomorrow.

 

[Captain FT]

LOL @ worm shot, thats awesome

Can't wait, I see sustain alpha is now available in worm shot, i'm going to try some.

Any plans to release Dermacrine in liqua-vade?

 

[Drewb]

Interesting...