I like 300 mg 2x/week. I metabolize it fast, and on weekly doses, I was seeing peaks & valleys (in mood and sex drive). my 2x/week plan is working well, and my doctor is good with it. (been covered in other threads, but I'm on HRT at this dosage. My levels are now in the middle of "normal" for my age group). I otherwise would be virtually at the level of a 5-year-old boy, if not for HRT. That's why the higher than normal doses for HRT.
Charles