I have an Exercise Science degree, and I just took my ACSM exam (I'll know how I did in a few weeks), and I plan to take the NSCA-Certified Strength and Conditioning Specialist exam. Those three things in conjunction will give you any job you want anywhere in the country that is related to fitness. Don't forget that getting just any old PT certification isn't going to equate to big money. Most gyms have certain certifications they look for.. ACSM, NSCA, ACE, and one or two others are typically accepted. NASM isn't bad. I don't know much about ISSA, but to my knowledge it isn't a toughie. And just because you have a cheapo easy certification doesn't necessarily mean you know your shit.. some people are smart enough to recognize that when looking for a trainer as well. This wasn't intended to turn anybody off or belittle them in any way.. just a friendly warning. Good luck with whatever path you choose!