PA and Par - 1-T Ethergels

[Bill Llewellyn]

a true battle of the minds

when will the ethergels be available to us, the oh so waiting and oh so willing public ?

They should be shipping in about 2 weeks, probably a little less now.

 

[Par Deus]

I will get back in more detail tonight, but for now, I do indeed concede that they should be better than plain ol' powder, but I don't, at this point, think the data is strong enough to say "far better", for all of the reasons mentioned in my post.

 

[Scatocephalus]

Would 1-AD be more bio-available if mixed with sesame oil before oral ingestion?

 

[1fast400]

Europa will have the gels.........????????

 

[Bill Llewellyn]

Europa will have the gels.........????????

Yes, Europa will have them..

 

[1fast400]

When will europa have them? Also, that is quite a statement to say they will equal out to a dermal product. Is there an estimation as to how many gels it will take to equal 100mg transdermally? Should a mg per mg assumption be made? From my customers experience 1-test ethers (sauce) are not even close to a mg per mg equal to a dermal. I've had many customers run 4-6 pills of sauce a day (300mg/450mg). Their results do not compare to my customers doing 100mg 2x a day of ONE. I'm just wondering at what point and what cost will these products equal out?

 

[Bill Llewellyn]

When will europa have them?

They have a shipment pending from the first lot. As soon as it is in, it is going out to them.

Also, that is quite a statement to say they will equal out to a dermal product. Is there an estimation as to how many gels it will take to equal 100mg transdermally? Should a mg per mg assumption be made?

I don't think we will ever really be able to say x number of gels = x mg of dermal and have everyone agree on it. Too many variables, and no way to get solid numbers. Plus, we still argue over the potency of other PH's. But I expect it to be close, but hopefully better for the gels still.

From my customers experience 1-test ethers (sauce) are not even close to a mg per mg equal to a dermal. I've had many customers run 4-6 pills of sauce a day (300mg/450mg). Their results do not compare to my customers doing 100mg 2x a day of ONE.

They probably should have used a delivery vehicle..

I'm just wondering at what point and what cost will these products equal out?

If the design works even half as well as I expect, I don't think there will be any complaints over the cost. Mg for Mg of hormone the two types of products should be relatively close in price anyway. I'd do the math and tell you exactly, but my brain is too fried for it, and I'm too lazy to open up calculator or get up for one.

- Bill

 

[pa1ad]

Sounds to me like a whole lot of trouble and expense to put the steroid into a soft gel cap with oil when you can probably get essentially the same effect by just taking the straight steroid caps with food containing some fat. Or am I missing something?

 

[Bill Llewellyn]

Sounds to me like a whole lot of trouble and expense to put the steroid into a soft gel cap with oil when you can probably get essentially the same effect by just taking the straight steroid caps with food containing some fat. Or am I missing something?

I think so, because that assumption is quite a stretch. Yes, a meal with some fat content would help steroid absorption, naturally, but this does not equate to dissolving a steroid directly in an oily carrier. There were striking differences between oils in the cited study even. For example, sesame oil and triolein were significantly more effective than monolein and oelic acid.

The “fatty meal” vehicle wasn’t tried in the experiment unfortunately, but I am doubtful it would have faired very well next to the other solutions.

- Bill Llewellyn

 

[Par Deus]

I think so, because that assumption is quite a stretch.

I agree with Bill on this, based on the conditions used in the studies. Though, I am obviously very skeptical about how much significance the studies will have in regard to real world usage because the conditions are so different.