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Oxytocin..yay or nay?

celica said:
I love it ... on my 3rd btl


What is the concentrated percentage of the compound in this product (OxyCalm)? I understand that this drug is by prescription however; if it's at a lower dose can it be sold without one? This compound sounds extremely promising in various areas concerning sex, attitude, personality, sexual bonding, and trusting issues. What is the best product that you could buy out there and what would be a regular diagnosis by a doctor before this is prescribed to you?
 
Ok, I must be an idiot because I have never heard of oxytocin being used for vanity reasons. I use to use it all the time on my cats when they were in labor. Why would a human use it other than to speed up contractions during child birth???
 
Fitness_Wendy said:
Ok, I must be an idiot because I have never heard of oxytocin being used for vanity reasons. I use to use it all the time on my cats when they were in labor. Why would a human use it other than to speed up contractions during child birth???
It's a pressure center hormone in humans. It has many applications.

From Wikepedia

Oxytocin is a peptide of nine amino acids (a nonapeptide). The sequence is cysteine - tyrosine - isoleucine - glutamine - asparagine - cysteine - proline - leucine - glycine (CYIQNCPLG). The cysteine residues form a sulfur bridge.

The structure of oxytocin is very similar to that of antidiuretic hormone, (also known as vasopressin), which is also a nonapeptide with a sulfur bridge. Oxytocin and antidiuretic hormone are the only known hormones released by the human posterior pituary gland.

Plays some role in orgasm – for both males and females. Oxytocin concentrations in the blood are significantly elevated in both sexes during sexual arousal and orgasm (Carmichael et al 1987). In males, oxytocin is said to facilitate sperm transport in ejaculation.

# Thought to induce pair bonding in people. Plasma concentrations of oxytocin have been reported to be higher amongst people who claim to be falling in love. It is also thought that oxytocin might mediate other forms of pair bonding such as friendship and family relationships as given above. Reduction of sociophobic behavior was shown after treatment with oxytocin. # Nasally-administered oxytocin appears to generate trust in humans. In a 2005 study, it was shown that in a risky investment game, experimental subjects given the hormone displayed what the researchers deemed "the highest level of trust" twice as often as the control group who were given placebos. The same experiment with the subjects told that they were interacting with a computer showed no such reaction, leading to the conclusion that oxytocin was not merely affecting risk-aversion (Kosfeld 2005)

# Nasally-administered oxytocin has been reported to reduce fear in humans and to reduce the activity of the amygdala (which contains a large number of oxytocin receptors and is in general thought to be responsible for fear responses). It is thus possible that oxytocin lowers fear by lowering amygdala activity. (Kirsch 2005)

# Various anti-stress functions: reducing blood pressure and cortisol levels, increasing tolerance to pain, reducing anxiety. Oxytocin may play a role in encouraging "tend and befriend", as opposed to "fight or flight", behavior, in response to stress.

# Oxytocin and oxytocin receptors are also found in the heart, and the hormone appears to play an important role in the embryonal development of the heart by promoting cardiomyocyte differentiation. (Paquin & Danalache 2002, Jankowski 2004)

# According to some studies in animals, oxytocin inhibits the development of tolerance to various addictive drugs (opiates, cocaine, alcohol) and reduces withdrawal symptoms. (Kovacs 1998)

Oxytocin is destroyed in the gastrointestinal tract and is therefore administered by injection or as nasal spray. Oxytocin given intravenously does not enter the brain in significant quantities - it is excluded from the brain by the blood-brain barrier. Drugs administered by nasal spray are thought to have better access to the CNS.
 
Ulter said:
It's a pressure center hormone in humans. It has many applications.

From Wikepedia

Oxytocin is a peptide of nine amino acids (a nonapeptide). The sequence is cysteine - tyrosine - isoleucine - glutamine - asparagine - cysteine - proline - leucine - glycine (CYIQNCPLG). The cysteine residues form a sulfur bridge.

The structure of oxytocin is very similar to that of antidiuretic hormone, (also known as vasopressin), which is also a nonapeptide with a sulfur bridge. Oxytocin and antidiuretic hormone are the only known hormones released by the human posterior pituary gland.

Plays some role in orgasm – for both males and females. Oxytocin concentrations in the blood are significantly elevated in both sexes during sexual arousal and orgasm (Carmichael et al 1987). In males, oxytocin is said to facilitate sperm transport in ejaculation.

# Thought to induce pair bonding in people. Plasma concentrations of oxytocin have been reported to be higher amongst people who claim to be falling in love. It is also thought that oxytocin might mediate other forms of pair bonding such as friendship and family relationships as given above. Reduction of sociophobic behavior was shown after treatment with oxytocin. # Nasally-administered oxytocin appears to generate trust in humans. In a 2005 study, it was shown that in a risky investment game, experimental subjects given the hormone displayed what the researchers deemed "the highest level of trust" twice as often as the control group who were given placebos. The same experiment with the subjects told that they were interacting with a computer showed no such reaction, leading to the conclusion that oxytocin was not merely affecting risk-aversion (Kosfeld 2005)

# Nasally-administered oxytocin has been reported to reduce fear in humans and to reduce the activity of the amygdala (which contains a large number of oxytocin receptors and is in general thought to be responsible for fear responses). It is thus possible that oxytocin lowers fear by lowering amygdala activity. (Kirsch 2005)

# Various anti-stress functions: reducing blood pressure and cortisol levels, increasing tolerance to pain, reducing anxiety. Oxytocin may play a role in encouraging "tend and befriend", as opposed to "fight or flight", behavior, in response to stress.

# Oxytocin and oxytocin receptors are also found in the heart, and the hormone appears to play an important role in the embryonal development of the heart by promoting cardiomyocyte differentiation. (Paquin & Danalache 2002, Jankowski 2004)

# According to some studies in animals, oxytocin inhibits the development of tolerance to various addictive drugs (opiates, cocaine, alcohol) and reduces withdrawal symptoms. (Kovacs 1998)

Oxytocin is destroyed in the gastrointestinal tract and is therefore administered by injection or as nasal spray. Oxytocin given intravenously does not enter the brain in significant quantities - it is excluded from the brain by the blood-brain barrier. Drugs administered by nasal spray are thought to have better access to the CNS.

So is this the actual drug or some homopathic preperation? I have seen "GH" spray sold and I'm sure it's not real GH so I'm curious as to the pharmacology of this drug
 
Ulter said:
It's a pressure center hormone in humans. It has many applications.

From Wikepedia

Oxytocin is a peptide of nine amino acids (a nonapeptide). The sequence is cysteine - tyrosine - isoleucine - glutamine - asparagine - cysteine - proline - leucine - glycine (CYIQNCPLG). The cysteine residues form a sulfur bridge.

The structure of oxytocin is very similar to that of antidiuretic hormone, (also known as vasopressin), which is also a nonapeptide with a sulfur bridge. Oxytocin and antidiuretic hormone are the only known hormones released by the human posterior pituary gland.

Plays some role in orgasm – for both males and females. Oxytocin concentrations in the blood are significantly elevated in both sexes during sexual arousal and orgasm (Carmichael et al 1987). In males, oxytocin is said to facilitate sperm transport in ejaculation.

# Thought to induce pair bonding in people. Plasma concentrations of oxytocin have been reported to be higher amongst people who claim to be falling in love. It is also thought that oxytocin might mediate other forms of pair bonding such as friendship and family relationships as given above. Reduction of sociophobic behavior was shown after treatment with oxytocin. # Nasally-administered oxytocin appears to generate trust in humans. In a 2005 study, it was shown that in a risky investment game, experimental subjects given the hormone displayed what the researchers deemed "the highest level of trust" twice as often as the control group who were given placebos. The same experiment with the subjects told that they were interacting with a computer showed no such reaction, leading to the conclusion that oxytocin was not merely affecting risk-aversion (Kosfeld 2005)

# Nasally-administered oxytocin has been reported to reduce fear in humans and to reduce the activity of the amygdala (which contains a large number of oxytocin receptors and is in general thought to be responsible for fear responses). It is thus possible that oxytocin lowers fear by lowering amygdala activity. (Kirsch 2005)

# Various anti-stress functions: reducing blood pressure and cortisol levels, increasing tolerance to pain, reducing anxiety. Oxytocin may play a role in encouraging "tend and befriend", as opposed to "fight or flight", behavior, in response to stress.

# Oxytocin and oxytocin receptors are also found in the heart, and the hormone appears to play an important role in the embryonal development of the heart by promoting cardiomyocyte differentiation. (Paquin & Danalache 2002, Jankowski 2004)

# According to some studies in animals, oxytocin inhibits the development of tolerance to various addictive drugs (opiates, cocaine, alcohol) and reduces withdrawal symptoms. (Kovacs 1998)

Oxytocin is destroyed in the gastrointestinal tract and is therefore administered by injection or as nasal spray. Oxytocin given intravenously does not enter the brain in significant quantities - it is excluded from the brain by the blood-brain barrier. Drugs administered by nasal spray are thought to have better access to the CNS.


Since there is only one reference to a man taking this and not a woman I have to ask this question now......if a woman takes it will it still give her uterine contractions no matter what?
 
Fitness_Wendy said:
Since there is only one reference to a man taking this and not a woman I have to ask this question now......if a woman takes it will it still give her uterine contractions no matter what?

I'd say save the oxytocin for post-partum hemmorhage; much like glutamine, it sounds like it's supposed to do a "lot" in theory, but doesn't deliver.
;)
 
Yes it works in a spray. That fact and the study showing it's effectiveness were written up in The New York Times, The Washington Post, The Wall St Journal and was on MSNBC. This is not some garbage GH in a spray product.
It does not cause contraction in women who are not birthing. It is not used in those doses when you use the spray. The studies done on oxytocin's effects were done with the exact amount used in the spray NOT the amount INJECTED into women for lactating and birthing purposes.

Posts:


http://www.elitefitness.com/forum/showthread.php?t=457702

http://www.elitefitness.com/forum/showthread.php?t=453246

http://www.elitefitness.com/forum/showthread.php?t=451476

http://www.elitefitness.com/forum/showpost.php?p=6016478&postcount=13

http://www.elitefitness.com/forum/showpost.php?p=6017015&postcount=14

For cycle libido loss.
http://www.elitefitness.com/forum/showpost.php?p=6074219&postcount=1


Two out of several studies showing what oxytocin does.

Carter, C.S.
Oxytocin and Sexual Behavior
Neuroscience and Biobehavioural Reviews 1992:16, 131-144

Carmichael, M.S. et al
Plasma oxytocin increases in human sexual response.
Journal of Clinical Endocrinology and Metabolism 1987:64, 27-31
 
OxyCalm is the best spray delivery of Oxytocin out there, bar none. I know for a fact that the Oxytocin used in OxyCalm comes from one of only 2 factories in the world that have approvals for Oxytocin use in both animals and humans. Of course, OxyCalm is not FDA approved, but the Oxytocin used in the preparation of OxyCalm is as pure as it gets.

Good stuff!
 
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