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Myostat by Biotest
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Triple J
New member
Most of the research in this area has focused on genetically modified mice. So wether the mice are altered as myostatin knock-outs, or to inhibit myostatin (through increased expression of say forstatin), the lab results came about in mice born with these characteristics.
I am not aware of any studies that demonstrate substances that can transform animals of normal genetics through inhibition of myostatin, say in adulthood. Well, it is not to say it is not possible, I just think that if it were as easy as that, we would have seen some studies or something more significant from the major drug companies. I would bet they are working on this but I just have a hard time believing that Biotest beat them to it.
And plus Biotest even says that the effects will be rather slow-acting (over say a year), so they are basically admitting this is just an experiment (since they have not done any real tests themselves - just rushed the thing to market based on some lab experiments). I'll even go so far as to say they know it will not work, if it were as powerful as they say, there would be too many risks in rushing it to the consumer.
Just think, what would it take to feed the supplement in high amounts to some mice to see the effects?
I am not aware of any studies that demonstrate substances that can transform animals of normal genetics through inhibition of myostatin, say in adulthood. Well, it is not to say it is not possible, I just think that if it were as easy as that, we would have seen some studies or something more significant from the major drug companies. I would bet they are working on this but I just have a hard time believing that Biotest beat them to it.
And plus Biotest even says that the effects will be rather slow-acting (over say a year), so they are basically admitting this is just an experiment (since they have not done any real tests themselves - just rushed the thing to market based on some lab experiments). I'll even go so far as to say they know it will not work, if it were as powerful as they say, there would be too many risks in rushing it to the consumer.
Just think, what would it take to feed the supplement in high amounts to some mice to see the effects?
Last edited:
J said:
Most of the research in this area has focused on genetically modified mice. So wether the mice are altered as myostatin knock
outs, or to inhibit myostatin (through increased expression of say
forstatin), the lab results came about in mice born with these
characteristics.
My reply:
Triple J, I was reading on the John Hopkins website about some scientists who were administering the protein Follastatin (which binds to myostatin) to mice in a lab setting; if I remember correctly, the mice eventually grew just like the "knock out" mice did.
BTW, you can buy follastatin protein from that same lab supply company that sells IGF-1 Long R3 . . . but it's hella expensive needless to say.
Most of the research in this area has focused on genetically modified mice. So wether the mice are altered as myostatin knock
outs, or to inhibit myostatin (through increased expression of say
forstatin), the lab results came about in mice born with these
characteristics.
My reply:
Triple J, I was reading on the John Hopkins website about some scientists who were administering the protein Follastatin (which binds to myostatin) to mice in a lab setting; if I remember correctly, the mice eventually grew just like the "knock out" mice did.
BTW, you can buy follastatin protein from that same lab supply company that sells IGF-1 Long R3 . . . but it's hella expensive needless to say.
Triple J
New member
Fortes said:
I meant to say follastatin in my message, at any rate, we are referring to the same research aricle - the mice were genetically engineered to produce higher than normal amounts of follastatin. So the follastatin was not being administered, it was naturally present in extraordinary amount from pre-birth forward.
Full grown adult males will not benefit from this product. Reduced myostatin levels, as mentioned before, are only going to help muscle wasting patients. This is something Pinnacle sent me to in reference to a question I asked:
First and foremost, we are not claiming that the compound in Juiced Protein (brown sea algae or "fraction C") totally inhibits Myostatin or is responsible for the "mighty mice" and "super bulls". This is only possible (currently) via genetic manipulation.
What we know for sure is that our "fraction C" binds to Myostatin in a chromatography column. That study was carried out only a few months ago by a scientist from the Univ of Madrid. Therefore, it will be some time before the data are published in a peer-reviewed journal. Second, there are TONS more questions than answers about Myostatin, fraction C, and muscle growth. We do have an experiment underway that is verifying whether muscle cells incubated with various concentrations of "fraction C" and Myostatin have increased growth rates.
This in vitro data is an important first step in clarifying the role of fraction C on muscle size in vivo (which will be tackled in a later study).
First and foremost, we are not claiming that the compound in Juiced Protein (brown sea algae or "fraction C") totally inhibits Myostatin or is responsible for the "mighty mice" and "super bulls". This is only possible (currently) via genetic manipulation.
What we know for sure is that our "fraction C" binds to Myostatin in a chromatography column. That study was carried out only a few months ago by a scientist from the Univ of Madrid. Therefore, it will be some time before the data are published in a peer-reviewed journal. Second, there are TONS more questions than answers about Myostatin, fraction C, and muscle growth. We do have an experiment underway that is verifying whether muscle cells incubated with various concentrations of "fraction C" and Myostatin have increased growth rates.
This in vitro data is an important first step in clarifying the role of fraction C on muscle size in vivo (which will be tackled in a later study).
smokinghawk
New member
cman said:
Damn! I'm in the wrong business--I've discovered an amazing new way to block the effects of those genetically-influences pesky brain cells. And it won't take a year to see results!
OVRTrainer
New member
cman said:
This is why whales are so "big"! LOL
Tha One CrumCake
New member
Tha thing with Biotest is if you use it, don't like it, call them with in 90 days and say you want your money back. They'll take care of it.
I'm going to use 2 months supply and see if I notice anything.
If nothing, then I'll call them up and say I want my money back.
Nothing to really stress over.
Basically I'm going to run it with a high protein diet.
Normally , me personally, with a high protien diet (400-430grams), I can gain 6-7lbs of solid muscle every month. In 2 months, while on a high protein diet, If I gain 20lbs vs. 12-14lbs, then I would say it's a good product.
I know my body, and I know what I'm capable of doing and what i'm not capable of doing.
I'll let you guys know my results. Either way in the next two months I'll be gaining 12-14lbs so I don't give a fuck. lol.
Peace
Crum
I'm going to use 2 months supply and see if I notice anything.
If nothing, then I'll call them up and say I want my money back.
Nothing to really stress over.
Basically I'm going to run it with a high protein diet.
Normally , me personally, with a high protien diet (400-430grams), I can gain 6-7lbs of solid muscle every month. In 2 months, while on a high protein diet, If I gain 20lbs vs. 12-14lbs, then I would say it's a good product.
I know my body, and I know what I'm capable of doing and what i'm not capable of doing.
I'll let you guys know my results. Either way in the next two months I'll be gaining 12-14lbs so I don't give a fuck. lol.
Peace
Crum
I've always been happy with most of the Biotest line myself. And I am going to give the Myostat a try. As The One Crumcake said, they have a money back guarentee and I have heard they do honor it.
As far as when to take it, you take one capsule in the morning with food and one capsule at night with food. Each capsule is 500 mg I believe. Three bottles last 2 months.
As far as when to take it, you take one capsule in the morning with food and one capsule at night with food. Each capsule is 500 mg I believe. Three bottles last 2 months.
Tha One CrumCake
New member
1fast400 said:
You make the assumption that Biotest won't honor the money back promise.
I've dealt with them before in these types of situations, and they've been good people.
I've actually had them call MY HOUSE to take care of it at their own will. Which I thought was cool.
Tha One CrumCake
New member
Re: Any guinea pigs yet?
I am the guinea. My package should arrive tommarow.
The best place to buy it would be Biotest due to the money back gaurantee offer they have.
3 Bottles cost $140.
I'll let you guys know the deal in 2 months. Peace.
u4ik_RAGE said:
I am the guinea. My package should arrive tommarow.
The best place to buy it would be Biotest due to the money back gaurantee offer they have.
3 Bottles cost $140.
I'll let you guys know the deal in 2 months. Peace.
young guns
New member
http://www.ast-ss.com/research/crib...tion=methoxy&SearchType=All&author=All&page=1
here's what AST had to say about myostatin inhibitors, just in case anyone's curious.
here's what AST had to say about myostatin inhibitors, just in case anyone's curious.
u4ik_RAGE
New member
I'm expecting this to be total crap but I'm going to try it anyway (next friggin' paycheck).
You really have nothing to lose with their money back guarantee. If it's crap, basicly you let Biotest hold your money for a couple months, then get it back.
2 good things will come out of me trying it:
1) When I say this is absolute worthless crap in 2 months I can do so having tried the full dosage for 2 months, not because someone else says it's crap
2) No placebo effects. If it works, I'll be shocked.
My diet and training is already solid, IMO, and this is the only variable.
On the other hand I may aquire a new genetic disorder that only comes with messing around with your predisposed genetic makeup
In that case I would be able to sue Biotest for millions along with all the other victims and put them out of business (damn, I wish it were Muscletech!!).
...Um, yeah... I think the worthless crap scenario is more likely.
You really have nothing to lose with their money back guarantee. If it's crap, basicly you let Biotest hold your money for a couple months, then get it back.
2 good things will come out of me trying it:
1) When I say this is absolute worthless crap in 2 months I can do so having tried the full dosage for 2 months, not because someone else says it's crap
2) No placebo effects. If it works, I'll be shocked.
My diet and training is already solid, IMO, and this is the only variable.On the other hand I may aquire a new genetic disorder that only comes with messing around with your predisposed genetic makeup
In that case I would be able to sue Biotest for millions along with all the other victims and put them out of business (damn, I wish it were Muscletech!!).
...Um, yeah... I think the worthless crap scenario is more likely.
Triple J
New member
Also keep in mind, the possibility, that something is in the product that will make you feel something. Some creatine, ephedrine, or something. The algae could have some effect like on the body. I mean with the BS stories these companies make up to hype these products it does not seem that much a stretch that they found an ingrediant that might do something, albeit not having anything to do with Myostatin or whatever. There just is no validity behind these marketing claims.
Travbedaman
New member
I`ll wait a year or so, for now I`ll stick to steroids.
Naturally Low Octane
New member
ok heres the deal. I have been taking myostat by biotest and pinnacle juiced protien. three scoops prot ed and 2 pills myostat. regardless of what all the naysayers may think this stuff is the real thing. after a week of taking it the next day after a shoulder workout i really felt like i could actually feel my delts growing. they were getting crazy tight and like pulsing it was wierd. i have new muscle coming up everywhere. not just muscle getting bigger but real new muscle that ive never seen before. im telling you this stuff is awesome. bump for the biological engineers who took the time to study this amazing protien and the effects of its inhibition.
another thing. why would u be sceptical whether it would work in adults, and not just from a genetic mutation? the research so far shows that myostatin aids in the regulation of muscle growth. are you telling me that adults dont have muscle growth?
another thing. why would u be sceptical whether it would work in adults, and not just from a genetic mutation? the research so far shows that myostatin aids in the regulation of muscle growth. are you telling me that adults dont have muscle growth?
doppelganger
New member
so Lo Octane, how long have you been taking Myostat? and do you think your results are from Myostat or Juiced Protein (what's in that btw?)
Just finished taking it for 2 months...
I did put on about 6 pounds and leaned up a bit, this wasn't enough of a result to justify spending $140.00.
I called Biotest today and they said that I wanted to they would send me 2 more months worth and if I still wasn't satisfied they would then refund my money...
Gotta give them props for the cool return policy.
PS. I will starting a cycle soon and from what biotest implies I should see good results from the combo.
Go Big-
RideHard
I did put on about 6 pounds and leaned up a bit, this wasn't enough of a result to justify spending $140.00.
I called Biotest today and they said that I wanted to they would send me 2 more months worth and if I still wasn't satisfied they would then refund my money...
Gotta give them props for the cool return policy.
PS. I will starting a cycle soon and from what biotest implies I should see good results from the combo.
Go Big-
RideHard
Nutri-Wrestler
New member
Lo octane. To answer your question about adults developing new muscles cells, no. Humans stop develpoing muscle cells at an early age, like around pre-teen age. After this age, muscle growth is through hypertrophy which is the adding of myofibrils to muscle cells to increase myofibril count.
if you wanna know how the muscles contract, go to this link:
http://www.howstuffworks.com/muscle.htm
Ross
if you wanna know how the muscles contract, go to this link:
http://www.howstuffworks.com/muscle.htm
Ross
Simple, because not even in animal research will you find anything that shows adult rats benefiting from reduced myostatin levels via a supplement. The results you seem from the animals in the mags are knockout rats. This is hardly the same as giving a rat a supplement to "reduce" myostatin.
It is real simple, results will be due to "placebo effect". When you spend as much money as these companies are wanting you too, I'm sure you'll eat a little better or train a little harder. These are the things that add up to results not some algae. Look up Cognitive Dissonance theory, it will help explain how people get results off this stuff.
feelin_kinda_saucey
New member
It is real simple, results will be due to "placebo effect". When you spend as much money as these companies are wanting you too, I'm sure you'll eat a little better or train a little harder. These are the things that add up to results not some algae. Look up Cognitive Dissonance theory, it will help explain how people get results off this stuff. [/B][/QUOTE]
EXACTLY WHAT HE SAID! I know when i spend alot of money on a cycle or some exspensive supplement, i train harder and eat better because i dont want to waste the time i have on the cycle or supp. because i would be wasting money and valuable time.... that is why you see some affect from these supps.... or at least i do.
EXACTLY WHAT HE SAID! I know when i spend alot of money on a cycle or some exspensive supplement, i train harder and eat better because i dont want to waste the time i have on the cycle or supp. because i would be wasting money and valuable time.... that is why you see some affect from these supps.... or at least i do.
riskybizz007
New member
I agree w/ the whole Placebo affect idea... I've read a few people posting good gains w/ for example Methoxy or ECDY which we all know is worthless. What happens, people tend to eat more calories, work out harder, eat cleaner, then say "oh yeah that shit kicks ass!"
There's very very few supplements out there that are actually worth a crap when it comes to muscle building. This Myostat seems like it will soon be on the same shelf as HMB, Methoxy, ECDY, Ribose, and Bee Pollen.
There's very very few supplements out there that are actually worth a crap when it comes to muscle building. This Myostat seems like it will soon be on the same shelf as HMB, Methoxy, ECDY, Ribose, and Bee Pollen.
