List of supplements that supposedly lower your SHBG levels!!

[lawnsaver]

what brand are you taking?

www.Beyond-a-century.com

$5.95 per 50 grams!!

 

[HighIntensity]

www.Beyond-a-century.com

$5.95 per 50 grams!!

same as I got bro, napped 7 bottles ...going to use that with nettle and Muira Puama

hey can't hurt for under 100 bucks

 

[Nelson Montana]

Lots of good points. Forgive me if I don't credit everyone for each statement.

I'm with Lawnsaver on the BAC Avena Sative. I tried "Action LAbs" brand and it did nothing. Used the BAC and I've got a pup tent going every morning ( and I'm 49), so it obviously isn't an inert substance. (Now if I can ony get the wife to blow revelry).

Morning wood is the best "non scientific" gauge of higher free T. I'd be curious to see some tests. Either way, I'm going to keep using it.

Didn't like the Nettles (Utica Diorca) because it lowers DHT which kills the libido highening effect.

I found Muama Puama to be effecive as well but evidence is scant, although the locals swear by it. Anecdotally increases ejaculate volume.

Here's one more: Catuaba. Some studies show it creases sperm count. Good for all you Deca users.

Proviron doesn't directly block estrogen.It competes with the aromatase enzyme.

Estrogen is a factor in SHBG, but not the sole factor. You can have low e-and high SHBG and vice versa.

Winstrol supposedly lowers SHBG, depending on who you want to believe, but I'd say it's speculative. Winny can't convert to estrogen which suggests it increases DHT which can't convert to estrogen yet has a high affinty for androgen receptor sites. So in theory, it should lower SHBG -- but the damn LDL elevation. No such problem with Proviron.

SHBG level is a genetic trait which increase with age. Why? Who the fuck knows? Everything gets less effecient with age. It could be the body wasn't meant to reproduce after the age of 30 or so. But even young men can have too much SHBG. It's like testosterone. Why does one guy have 400 and another guy has 900? And realize, all this is just a piece of the puzzle. The process of anabolism is more than ones testosterone levels. That's why someoe can take enough cyp so that they have 100X's the testosterone of a natural athlete, yet the natural athlete can put on more muscle. There's so much we don't know.

And yes. Clomid has been shown to increase SHBG. It's also been shown to lower it. So go figure. I believe the former. Clomid is a libido killer in about half of the people who use it. Proviron is a much better choice for post short cycle and HCG is a much better choice post long cycle. Clomid blows.

 

[HighIntensity]

Nelson your right about nettle I use to use it to keep my hair.

What about Maca? I love this herb.

 

[lawnsaver]

"Clomid blows" wow, thats a strong statement!! Why is HCG a better choice than clomid? HCG, to my knowledge doesnt restart one's HPTA. Correct me if I'm wrong. It only signals the LC to produce more LH. Once the "signal" fades when you stop, so does the production of test from your testicles. And what about the high conversion rate of test to estrogen that HCG produces? Wouldnt that hinder recovery?

Nelson please school me!

 

[Nelson Montana]

Whether you use Clomid or HCG there comes a time when your own HPTA has to take over. HCG only cushions the blow. Clomid does so in some people, not in others, and for many, it makes the situation worse, they just don't know it. The estrogen from HCG can be avoided by taking smaller interspersed dosages -- and using --what else? -- Proviron.

Yeah, Maca's good too, although I don't think it affects testosterone. Oddly enough, it's been shown to improve thyroid function. (!)

 

[plornive]

Whether you use Clomid or HCG there comes a time when your own HPTA has to take over. HCG only cushions the blow. Clomid does so in some people, not in others, and for many, it makes the situation worse, they just don't know it. The estrogen from HCG can be avoided by taking smaller interspersed dosages -- and using --what else? -- Proviron.

Yeah, Maca's good too, although I don't think it affects testosterone. Oddly enough, it's been shown to improve thyroid function. (!)

Hey Nelson, does Nolvadex do anything to SHBG? If I take 20mg Nolvadex while using dbol for a while to prevent gyno, will I also be increasing SHBG?

 

[Punschkrapfen]

Re: Re: Re: Re: What elevates SHBG?

Where is the data showing the effects proviron has on SHBG?

the only study i know of compares the binding affinity of various steroids to SHBG in rats and there, mesterolone (Proviron) did bind much stronger than all other compounds, including DHT, testosterone and nandrolone to SHBG, but less strongly to the AR compared to the other androgens:

Endocrinology 1984 Jun;114(6):2100-6

Relative binding affinity of anabolic-androgenic steroids: comparison of the binding to the androgen receptors in skeletal muscle and in prostate, as well as to sex hormone-binding globulin.

Saartok T, Dahlberg E, Gustafsson JA.

It is unclear whether anabolic steroids act on skeletal muscle via the androgen receptor (AR) in this tissue, or whether there is a separate anabolic receptor. When several anabolic steroids were tested as competitors for the binding of [3H]methyltrienolone (MT; 17 beta-hydroxy-17 alpha-methyl-4,9,11-estratrien-3-one) to the AR in rat and rabbit skeletal muscle and rat prostate, respectively, MT itself was the most efficient competitor. 1 alpha-Methyl-5 alpha-dihydrotestosterone (1 alpha-methyl-DHT; mesterolone) bound most avidly to sex hormone-binding globulin (SHBG) [relative binding affinity (RBA) about 4 times that of DHT]. Some anabolic-androgenic steroids bound strongly to the AR in skeletal muscle and prostate [ RBAs relative to that of MT: MT greater than 19-nortestosterone ( NorT ; nandrolone) greater than methenolone (17 beta-hydroxy-1-methyl-5 alpha-androst-1-en-3-one) greater than testosterone (T) greater than 1 alpha-methyl-DHT]. In other cases, AR binding was weak (RBA values less than 0.05): stanozolol (17 alpha-methyl-5 alpha- androstano [3,2-c]pyrazol-17 beta-ol), methanedienone (17 beta-hydroxy-17 alpha-methyl-1,4-androstadien-3-one), and fluoxymesterolone (9 alpha-fluoro-11 beta-hydroxy-17 alpha-methyl-T). Other compounds had RBAs too low to be determined (e.g. oxymetholone (17 beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one) and ethylestrenol (17 alpha-ethyl-4- estren -17 beta-ol). The competition pattern was similar in muscle and prostate, except for a higher RBA of DHT in the prostate. The low RBA of DHT in muscle was probably due to the previously reported rapid reduction of its 3-keto function to metabolites, which did not bind to the AR [5 alpha-androstane-3 alpha, 17 beta-diol and its 3 beta-isomer (3 alpha- and 3 beta-adiol, respectively)]. Some anabolic-androgenic steroids (only a few synthetic) bound to SHBG (1 alpha-methyl-DHT much greater than DHT greater than T greater than 3 beta-adiol greater than 3 alpha-adiol = 17 alpha-methyl-T greater than methenolone greater than methanedienone greater than stanozolol). The ratio of the RBA in rat muscle to that in the prostate (an estimate of the myotrophic potency of the compounds) was close to unity, varying only between about 0.4 and 1.7 in most cases

 

[arigold]

Winstrol lowers the SHBG.........

To me is the better choice.......,but conterfeit are a problem......

 

[Silent Method]

SHBG level is a genetic trait which increase with age. Why? Who the fuck knows?

Sex differences in the control of sex-hormone-binding globulin in the elderly: role of insulin-like growth factor-I and insulin.

Lecomte P, Lecureuil N, Lecureuil M, Lemonnier Y, Mariotte N, Valat C, Garrigue MA
Eur J Endocrinol 1998 Aug 139:178-83

Abstract
OBJECTIVE: Serum levels of sex-hormone-binding globulin (SHBG) have been reported in the literature to increase with age in both sexes. We have investigated the variations in levels of androgens, insulin and IGF-I with age and have evaluated their putative roles to obtain a better understanding of the increase in SHBG. DESIGN: Cross-sectional pilot study of blood samples in healthy elderly subjects aged 50 to 90 years. PATIENTS AND METHODS: Forty-four postmenopausal women and 40 men were classified into three age groups. Subjects who were obese, undernourished or smokers and postmenopausal women receiving hormone replacement therapy were excluded from the study. Body mass index and waist/hip ratio were evaluated in each subject. Fasting levels of blood glucose, insulin, triglycerides, cholesterol, SHBG, testosterone, dehydroepiandrosterone sulfate (DHEAS) and IGF-I were measured. Free testosterone and glucose/insulin ratio were calculated. RESULTS: The results are based on variance analysis of the mean of each parameter in the three age groups. Multiple regression analysis was performed to define the role of age, insulin and IGF-I in the increase in SHBG. The increase in SHBG with age in older men was significant but that in postmenopausal women was not. Decreasing DHEAS with age was confirmed. No significant variations in glucose and insulin were observed with age in our selected population. A positive correlation was observed between insulin and triglycerides in elderly men and women. IGF-I decreased significantly with age in both sexes. Insulin was the main factor explaining SHBG increase with age in women. In men, both age and IGF-I contributed to the SHBG increase. CONCLUSIONS: The factors regulating the increase in SHBG with age appear to be different in the two sexes. Insulin plays a major role in women, whereas a decrease in IGF-I is the predominant regulating factor in men. These results should be thought of as a working hypothesis rather than a reflection of physiology.

Of course this does not explain everything related to age and sHBG, but once again we see that insulin and IGF-I are big peices of the SHBG level puzzle.