My wife is telling me as I type this that it definitely increases sex drive (course I noticed when on, just sayin) energy, elevated mood and motivation. Side effects included maybe some headaches, swelling of the clitoris, swelling of the breasts and nipple tenderness and after being on for two months a scratchy throat. The throat thing went away soon after stopping the cycle. The test we had still had some estrogen in it, which I believe caused the headaches, swelling of the breasts and nipple tenderness. Funny thing though, seemed to kick the shit out of her crohns. I believe the breast issues and headaches were caused by the estrogen in the mix. You shouldn't have that problem with the good stuff (pharm grade). Wife was using about 12 mg a week if I remember correctly. I would suggest lower if you plan on staying on for some time.