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napsgear
genezapharmateuticals
domestic-supply
puritysourcelabs
Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

L-How many mgs of L-Phenylalanine vitamin b6 for depresssion should I take??

Uber_Tool

New member
HELLO ALL: I just baught in the GNC L-Phenylalanine and vitamin b-6 and 5-HTP (tryptophan) to increase the production of dopamine, serotonin and noradrenaline. I just wanna know what is the best way to take all these supplements to lift moods. What is the best combination to get the best results??
Thanx all

Uber_Tool
 
It is an individual thing start low and slowly adjust up every few days until the desired effect is reached (like one pill of each on empty stomach). Or for some fun try a large dose to start to see what that feels like and then reduce. You'll need to experiment some no matter what, adjusting the dose from time to time as conditions warrant. Of ,and some DMAE may be a good idea, too.

You may want to take the phenalinine morning and the 5-htp night. This is individual as well, but the idea is to better support circadian patterns, stimulating serotonin at bedtime, and dopamine/noradrenaline daytime.

I'm not sure if that answer was what you are looking for but I think that is the bottom line.
 
Thankx a lot (I will try that) ;-)

HELLO: How are you? Well, thanks a lot i will try to see if it works: 500 mgs of L-Phenylalanine, 100 mgs of B6 in the morning to elevate dopamine/noradrenaline levels and then 5-HTP (50 mgs. at night after dinner) to increase serotonin levels and it even suppresses hunger cravings a little bit, well i hope this works in my path to feeling better and more positivie ;-p

Uber_Tool


"I will break the door of hell and smash the bolts; I will summon the dead to eat food with the living, and the living shall be outnumbered by the host of them." -The Epic of Gilgamesh
 
Regarding these supplements, take on an empty stomach, so either right before bed or first thing in the morning. The B6 dose sounds a little high to me but see what you think. Good luck
 
Do any of these supplements interact with Zoloft? I'm aware that Zoloft works with serotonin, but that's about the extent of my knowledge.
 
You would be better off taking Tyrosine instead of the phenylalanine since Phe is converted to Tyr in its own degradational pathway. Here's what the breakdown looks like:

Phenylalanine-->Tyrosine-->->->DOPA-->Dopamine-->Norepinephrine-->epinephrine.

As you can see, you could just substitute the Tyrosine in for the phe. Also, and i don't know how much Phe is supplement wise, but I know at places like Wal-Mart, Tyr can be easily obtained for about $4.00. Also, since Tyrosine is considered as a limiting amino acid in the body, it is only created from Phenylalanine when it is in low concentrations (semiessential aa). Therefore, the conversion of Phe-->Tyr would be even less efficient at producing catecholemines.

Tryptophan is a little more complicated in its pathways, but it can generate serotonin, niacin generation, and melatonin, etc. Basically, serotonin can be synthesized from Trp through decarbolylation.

Handsome Pete: I am no expert when it comes to SSRI's so if anyone out there sees that I am wrong, PLEASE correct my ass. Here is my answer though: If i am correct, Zoloft is used as a RE-uptake inhibitor for the blockage of serotonin (neurotransmitter)/norepinephrine. Therefore, you will have higher concentrations of these transmitters in the synapses of the nerve terminals, which is what I believe is the goal. I do not know if it will be overkill or how much or how little should be taken. In other words, since this is not really my "area", then I would suggest you ask someone like MS, par deus, Pat, macro, or cockdezl...they would probably be better suited for your answer on this subject of SSRI's.

MR. BMJ
 
Thanx a lot ;-)

HELLO: THanks a lot for your very extended explanation about the effects of Phenylalanine, well i guess you're right, I was taking Phenylalanine along witn b6 and I didn't really see any improvements in my moods, in fact I felt more irritable and nervous i guess from the excess of noradrenaline, i think that what i need is more serotonin, for it's calming and anxiety killing effects ;-)

have a nice day

Uber_Tool
 
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