I think it depends
Many factors to consider. How frequent you work each body part, your diet, the timing of your meals and the intensity of the running. Running takes a bigger toll on your body, then a stationary bike/rowing machine/stair climber/elliptical machine, because it places stress not only on your muscles, but your ligaments, tendons and bones. If you're not used to running, ease into it slowly. If you can run pretty well without any problems, then just watch how fast you go. A lot of people like me, don't really watch for it. I'm used to running for distance (a number of miles) instead of monitoring how long I run for, so I can go too hard within 20 minutes of running and stop before I reach the 30 minute mark. Just don't run before your leg routine. Some people sprint for a certain distance in their runs. Just remember that sprinting is anaeroblic, like weight lifting. You can tell not only by how sore your legs can get, but by the body composition of Sprinters and long distance runners. Sprinters look very muscular and cut while long distance runners look soft.